The settlement alleges that the company misrepresented its antiplatelet drug, Aggrenox, that was effective for many conditions 'below the neck,' such as heart attacks and congestive heart failure, and that it was superior to Plavix, without evidence to substantiate that claim; misrepresented that Micardis protected patients from early morning strokes and heart attacks and treated metabolic syndrome; misrepresented that Combivent
could be used as a first-line treatment for bronchospasms associated with chronic obstructive pulmonary disease (COPD); Falsely stated that Atrovent and Combivent
could be used at doses that exceeded the maximum dosage recommendation in the product labelling and that the drugs were essential for treatment of COPD.
Y.E.'ye pnomotoraks nedeniyle uygulanan bilateral torakotomi sonrasi 1gr sefazoline ampul (cefazol ampul), asetil sistein (Asist ampul) ipratropium Bromur Monohidrat Salbutamol Sulfat (Combivent
One of the major complains of patient was the shortness of breath lately; the patient was prescribed a combivent
combination inhaler to control her shortness of breath (table 2).
Concentrations of [[beta].sub.2]-agonists and IB in commercially available products in SA Product name Constituents Adco-Combineb IB 500 [micro]g, salbutamol 2.5 mg/2.5 ml Adco-Nebrafen IB 500 [micro]g, fenoterol 1.25 mg/4 ml Combivent
IB 500 [micro]g, salbutamol 2.5 mg/2.5 ml Duolin IB 500 [micro]g, salbutamol 2.5 mg/2.5 ml IB = ipratropium bromide.
, which comes in a metered dose inhaler containing both ipratropium bromide and albuterol, seems to be beneficial for many patients with this disease.
The DOJ announced yesterday that Boehringer will pay $95 million to resolve the allegations that it improperly promoted its anti-stroke drug Aggrenox, its chronic obstructive pulmonary disease drugs Atrovent and Combivent
, and its hypertension drug Micardis.
The product, marketed as Combivent
Respimat inhalation spray, does not contain chlorofluorocarbons (CFCs) and "is a suitable alternative for patients who are currently using Combivent
(ipratropium bromide and albuterol sulfate) inhalation aerosol," according to the statement, issued by the Division of Drug Information (DDI) in the FDA's Center for Drugs, Evaluation and Research (CDER).
The drugs include the short-acting anticholinergic ipratropium (Atrovent, Combivent
) and long-acting tiotropium (Spiriva).
, another popular treatment, will be phased out by the end of 2013.
Examples albuterol/VENTOLIN, PROVENTIL, COMBIVENT
epinephrine/PRIMATENE MIST montelukast/SINGULAIR theophylline/SLO-BID, THEO-DUR, THEO-DUR 24, UNIPHYL
Medications prescribed were: Beclazone (250 mcg), theophylline (200 mcg/300mg), Ventolin (1-4 puffs), and/or Atrovent/ Combivent
(1-2 puffs) as required.