combined immunodeficiency

(redirected from Combined immunodeficiencies)
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com·bined im·mu·no·de·fi·cien·cy

immunodeficiency of both B and T lymphocytes.

com·bined im·mu·no·de·fi·cien·cy

(kŏm-bīnd' im'yū-nō-dĕ-fish'ĕn-sē)
Immunodeficiency of both the B-lymphocytes and T-lymphocytes.


a deficiency in the immune system, either that mediated by antibody or T lymphocytes, or both. See also agammaglobulinemia, hypogammaglobulinemia, feline immunodeficiency virus, bovine immunodeficiency virus.

acquired immunodeficiency
see immune deficiency disease.
cancer-associated immunodeficiency
in general, associated with cachexia and debilitation, and also related to the type of neoplasia. Tumor-related effects on the immune system include impaired function of lymphocytes, altered cytokine production and activation of suppressor cell functions.
combined immunodeficiency
common variable immunodeficiency
a term encompassing a heterogeneous group of syndromes, which may be inherited or acquired, characterized by recurring persistent infections and deficiencies of some of the immunoglobulin classes.
congenital immunodeficiency
see immune deficiency disease.
immunodeficiency disease
iatrogenic immunodeficiency
secondary immune deficiency disease.
severe combined immunodeficiency
X-linked immunodeficiency
an inherited form of severe combined immunodeficiency has been reported in dogs. Puppies fail to grow and die from overwhelming infections at an early age.
References in periodicals archive ?
OPV immunization has been associated with poliovirus infection in patients with primary antibody deficiencies and combined immunodeficiencies, which can lead to paralysis (7,8).
Octagam is indicated for treatment of primary humoral immunodeficiency (such as congenital agammaglobulinemia), common variable immunodeficiency, X-linked agammaglobulinemia, Wiskott-Aldrich syndrome, and severe combined immunodeficiencies.
Other combined immunodeficiencies are part of well-defined immunodeficiency syndromes (e.
Of 946 patients with primary immunodeficiency, including 29 with severe combined immunodeficiencies, diagnosed from 1980 through 2006 at the Children's Memorial Health Institute in Warsaw, adverse events after BCG vaccination were observed in 16 (8,9).

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