colony-forming unit


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colony-forming unit

a unit of cells in bone marrow capable of generating or increasing the proliferation of new blood cells.

col·o·ny-form·ing u·nit

(CFU) (kol'ŏ-nē-fōrm'ing yū'nit)
1. A stem cell in culture capable of proliferating and differentiating into more mature cells. If the CFU is committed to a specific cell line, it is designated by an additional letter to indicate its commitment; e.g., CFU-E is committed to erythroid maturation; CFU-GM is committed to granulocyte-monocyte maturation.
2. Term used in microbiology to designate a colony formed from a single bacterium or fungus.
References in periodicals archive ?
When blood supply to the heart is blocked during a heart attack, cardiac colony-forming unit fibroblasts replace damaged tissue with collagen-based scar tissue.
This plant-based powder provides 20 grams of protein per serving and includes mineral-rich superfoods and greens; 6 billion colony-forming unit probiotics; and four digestive enzymes.
These cells are called cardiac colony-forming unit fibroblasts (cCFU-Fs).
For the study, published in the journal Heart Lung and Circulation, researchers used mouse models to investigate the impact of 1,25D -- a form of Vitamin D that interacts with hormones -- on the cardiac colony-forming unit fibroblasts (cCFU-Fs)cells that form scar tissue after a heart attack.
Caption: Figure 2: Results of colony-forming unit (CFU) assay and cell proliferation analysis.
The only cell functionality test presently used in this field, especially for umbilical cord blood transplantation, is the colony-forming unit (CFU) assay, which is subjective, non-validated and has been used since the early 1970s.
Topics include a method to isolate and purify human bone marrow stromal stem cells, adipose-derived stem cells, colony-forming unit assays for MSCs, freezing and recovery of MSCs, and assays of MSCs with microrrays.
The most common functional in vitro assay currently available for prediction of engraftment is the so-called colony-forming unit (CFU) assay in which cells are cultivated in a semiviscous methyl cellulose media enriched with various haematopoietic growth factors [11].
All of the tests detected the presence of as low as 1 colony-forming unit of E.
The number of colony-forming unit equivalents per ml in tracheal swabs from experimentally infected birds could be determined from a single sample.
Transfer frequencies were expressed as the number of transconjugants per donor colony-forming unit after the mating period.

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