colony-forming unit


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colony-forming unit

a unit of cells in bone marrow capable of generating or increasing the proliferation of new blood cells.

col·o·ny-form·ing u·nit

(CFU) (kol'ŏ-nē-fōrm'ing yū'nit)
1. A stem cell in culture capable of proliferating and differentiating into more mature cells. If the CFU is committed to a specific cell line, it is designated by an additional letter to indicate its commitment; e.g., CFU-E is committed to erythroid maturation; CFU-GM is committed to granulocyte-monocyte maturation.
2. Term used in microbiology to designate a colony formed from a single bacterium or fungus.
References in periodicals archive ?
For the study, published in the journal Heart Lung and Circulation, researchers used mouse models to investigate the impact of 1,25D -- a form of Vitamin D that interacts with hormones -- on the cardiac colony-forming unit fibroblasts (cCFU-Fs)cells that form scar tissue after a heart attack.
The only cell functionality test presently used in this field, especially for umbilical cord blood transplantation, is the colony-forming unit (CFU) assay, which is subjective, non-validated and has been used since the early 1970s.
Topics include a method to isolate and purify human bone marrow stromal stem cells, adipose-derived stem cells, colony-forming unit assays for MSCs, freezing and recovery of MSCs, and assays of MSCs with microrrays.
When we took a post-bacterial sample we ended up with only one colony-forming unit.
All of the tests detected the presence of as low as 1 colony-forming unit of E.
The number of colony-forming unit equivalents per ml in tracheal swabs from experimentally infected birds could be determined from a single sample.
Solicitation: Automated and standardized colony counting for the hematopoietic colony-forming unit (cfu) assay
Transfer frequencies were expressed as the number of transconjugants per donor colony-forming unit after the mating period.
Six samples were detected to have a total legionella count at or above the upper threshold, which is 1 000 colony-forming units per millilitre.
As you may know, the D-10 value for a microorganism is defined as the UV dose necessary to affect a 90% reduction in colony-forming units (CFUs).
As previously mentioned, the most common source of contamination is from people; a fully gowned operator may release as many as 10,000 colony-forming units per hour.

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