colony-forming unit

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colony-forming unit

a unit of cells in bone marrow capable of generating or increasing the proliferation of new blood cells.
Farlex Partner Medical Dictionary © Farlex 2012

col·o·ny-form·ing u·nit

(CFU) (kol'ŏ-nē-fōrm'ing yū'nit)
1. A stem cell in culture capable of proliferating and differentiating into more mature cells. If the CFU is committed to a specific cell line, it is designated by an additional letter to indicate its commitment; e.g., CFU-E is committed to erythroid maturation; CFU-GM is committed to granulocyte-monocyte maturation.
2. Term used in microbiology to designate a colony formed from a single bacterium or fungus.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Cells cultured for 4 days under different conditions were cultured for 6 additional weeks in long-term culture-initiating cell (LTC-IC) assays, and colony-forming cell (CFC) assays were then performed (n = 3, * p <0.05).
Mead et al., "In vitro hyperglycemia or a diabetic intrauterine environment reduces neonatal endothelial colony-forming cell numbers and function," Diabetes, vol.
Colony Forming Cell Assay.--The colony-forming cell assay is an in vitro assay used in the study of stem cells.
Colony-forming cell assays are helpful to assess functional activity of the downstream developmental stage, and under our particular myeloid-culture conditions, the myeloid potential was examined.
The effect of VEGF on GBSCs proliferation was tested by Neural Colony-Forming Cell Assay.
[4] Nonstandard abbreviations: HSPC, hematopoietic stem and progenitor cell; MNC, mononuclear cell; rhP/Fc, recombinant human P-selectin/Fc chimera; HBSS, Hanks balanced salt solution; MRE, microrenathane tube; PE, phycoerythrin; sP, P-selectin; CFC, colony-forming cell; BFU-E, burst-forming unit, erythroid; CFU-GM, colony-forming unit, granulocyte-macrophage.
Schofield, "The relationship between the spleen colony-forming cell and the haemopoietic stem cell," Blood Cells, vol.
Schofield, "The relationship between the spleen colony-forming cell and the hemopoietic stem cell," Blood Cells, vol.
After 5 days of expansion, cells were subjected to liquid culture differentiation and colony-forming cell assay as below.
The vasoreparative potential of endothelial colony-forming cells in the ischemic retina is enhanced by cibinetide, a nonhematopoietic erythropoietin mimetic.
Recent evidence illuminates the presence of two EPC subtypes: endothelial colony-forming cells (ECFCs) and early outgrowth cells (EOCs).
The researchers studied a special population of cells, known as endothelial colony-forming cells, found in cord blood, bone marrow and circulating blood.

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