colony-forming unit

(redirected from Colony-forming cell)

colony-forming unit

a unit of cells in bone marrow capable of generating or increasing the proliferation of new blood cells.

col·o·ny-form·ing u·nit

(CFU) (kol'ŏ-nē-fōrm'ing yū'nit)
1. A stem cell in culture capable of proliferating and differentiating into more mature cells. If the CFU is committed to a specific cell line, it is designated by an additional letter to indicate its commitment; e.g., CFU-E is committed to erythroid maturation; CFU-GM is committed to granulocyte-monocyte maturation.
2. Term used in microbiology to designate a colony formed from a single bacterium or fungus.
References in periodicals archive ?
The colony-forming cell assay is an in vitro assay used in the study of stem cells.
HemoGenix was the first company to provide a fully standardized ATP-based, in vitro bioluminescence assay system designed specifically as an alternative to, and in most cases a replacement for, the colony-forming cell (CFC) assay used to detect stem and progenitor cells of the blood-forming system.
By combining a traditional approach for examining stem cell differentiation with a fluorescent tool for measuring proliferation, HemoGenix provides a way to standardize and validate the widely-used stem cell colony-forming cell differentiation assay.
Results: Our results showed that the Vivo nanofat contained a large number of colony-forming cells.
While the body has cells that specialize in repairing blood vessels and creating new ones, called endothelial colony-forming cells, these cells can lose their ability to proliferate into new blood vessels as patients age or develop diseases like peripheral arterial disease, said Mervin C.
The researchers studied a special population of cells, known as endothelial colony-forming cells, found in cord blood, bone marrow and circulating blood.
Especially in the case of ESC freezing that employed only small number of colony-forming cells are provided for the cryopreservation, however, the simplified program ought to further be optimized for increasing post-thaw survival (Miyamoto et al.
After 14 d of incubation, colony-forming cells (CFCs) were counted under an inverted microscope and photographed.
7-fold increase in CD34 + cell count, a 3-fold increase in colony-forming cells, and 50-90-fold increase in short-term repopulating cells in G-BM, when compared to SS-BM.
Washington, July 20 ( ANI ): Endothelial colony-forming cells (ECFCs) derived from human placenta are better for forming blood vessels than the ECFCs derived from umbilical cord blood, according to a new study.
Endothelial colony-forming cells (ECFCs) derived from human placenta are more proliferative and better for forming new blood vessels than those derived from human umbilical cord blood, a study has found.

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