Severely disabled Liam, who had the extremely rare condition centronuclear myopathy and was under the care of the Newcastle Royal Victoria Infirmary adult home ventilation team, died on August 11, 2016, during what should have been a routine home administration of the antibiotic colomycin. His inquest at Teesside Coroners' Court heard evidence that he died from an anaphylactic shock from the colomycin being administered.
The hearing focused on the possible effects of the colomycin, which had been re-prescribed for Liam after a gap of several years, and whether it had been properly administered.
The commercial formulation colistin methanesulfonate sodium (CMS) which is used for systemic applications12 prepared by Forest laboratories, United Kingdom (Colomycin
) was imported.
Bacteriologic culture of a tracheal aspirate grew Acinetobacter baumannii, which was only susceptible to colomycin
Some groups of antibiotics are also known to have an acute toxic effect on the kidney, particularly aminoglycosides (such as tobramycin), and also colomycin
In conjunction, Forest Laboratories Europe has marketed a nebulised form of colistimethate sodium, an antibiotic used to treat the principal bacterial infections in cystic fibrosis patients, under the brand name Colomycin
, in the UK and Ireland.
Bacteria that contain NDM-1 are resistant to antibiotics currently available, with the exception of tigecycline (Tygacil) and colistin (Colomycin
), according to an article in the September 2010 issue of The Lancet.
Four years' experience of intravenous colomycin
in an adult cystic fibrosis unit.
The hearing also focused on the possible effects of the antibiotic colomycin
, which had been re-prescribed for Liam after a gap of several years, and whether it had been properly administered.
On the day of the tragedy, Thursday, August 11, Liam was given colomycin
at home by a consultant.
Mr Lineham's argument centres on claims she was discharged from Middlesbrough's James Cook University Hospital respiratory ward in March 2001 without her prescribed drug, Colomycin
Mr Lineham said she was discharged from Middlesbrough's James Cook University Hospital respiratory ward in March 2001 without her prescribed drug, colomycin
. He said: "When staff discovered this, they advised her GP at the Garth Surgery to supply it.