Coexistence of papillary and medullary carcinoma of the thyroid gland-mixed or collision tumour
? Clinicopathological analysis of three cases.
Cases not satisfying the histopathological criteria outlined by the 2017 World Health Organization classification of Odontogenic Tumours, Hybrid Odontogenic Tumours/ Collision tumour
, OKC associated with Nevoid Basal cell syndrome were grouped under exclusion criteria.
The multiclonal theory, on the other hand, states that the sarcomatoid carcinoma is a collision tumour
composed of the derivatives of two or more stem cells of separate epithelial and mesenchymal origin [18, 19].
One proposes that the neoplasm is essentially a collision tumour
, arising from a separate epithelial precursor and a distinct mesenchymal component.
The differential diagnoses include collision tumour
of meningioma and plasmacytoma, inflammatory pseudotumour, idiopathic hypertrophic pachymeningitis (IHP), and intracranial plasma cell granuloma.
Most cases with concomitant tumours had discrete RCC and AML areas within the same kidney (collision tumour
) or had synchronous occurrence of RCC in one kidney and AML in the other kidney.
We had one case of collision tumour
in 50 years old female and the histopathology was papillary serous cystadenocarcinoma in left ovary and in right ovary squamous cell carcinoma arising from dermoid cyst and foci of papillary serous cystadenocarcinoma.
Granell, "Large cell neuroendocrine --Adenocarcinona mixed tumour of colon: collision tumour
with peculiar behaviour.
Differential diagnoses are SCC, Collision tumour
consisting of SCC and Carcinoma ex-PA.
A rare case of collision tumour
was reported in our study, which showed two components of serous cystadenoma and mature cystic teratoma.
When the transition zone is not present, the staining suggests the presence of collision tumours
, as SCCs are typically negative for BerEP4 ; however, the lack of transition zone is not diagnostic .