CHAT

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CHAT

A gene on chromosome 10q11.2 that encodes choline acetyltransferase, which binds acetylCoA to choline, controlling acetylcholine production at the synapses of the autonomic nervous system, muscle and the sympathetic nervous system.

Molecular pathology
Polymorphisms of CHAT have been associated with choline acetyltransferase depletion in Alzheimer’s disease and cognitive impairment; CHAT mutations are associated with congenital myasthenic syndrome associated with episodic apnoea.
References in periodicals archive ?
netGuru will continue its Web4 collaborative software operations, information technology, and engineering business process outsourcing services businesses.
SunGard's financial systems business is adopting a new paradigm for collaborative software development patterned on the Open Source model which enables its product development teams around the world to share, contribute to, and leverage each other's work.
The distributed nature of Web services perfectly aligns with the concept of collaborative software development that CollabNet supports and which TCS is now implementing.
netGuru will retain its collaborative software operations and products, including eReview and ForReview, and its information technology and engineering business process outsource services businesses.

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