Cold agglutinins
Cold agglutinins
Antibodies that cause clumping of red blood cells when the blood temperature falls below normal body temperature (98.6°F/37°C).
Mentioned in: Cold Agglutinins Test
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References in periodicals archive
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6] If cold agglutinins were suspected, the sample was collected and immediately incubated at 37[degrees]C and at room temperature for 30 mins.
Cold agglutinins react with human red cells but they differ in the strength of the reaction with different cells.
3,9) Laboratory abnormalities including cryoglobulinemia, cold agglutinins, rheumatoid factor, and antineutrophilic antibody also are seen in children; (6,10) however, there are no reports of childhood pernio being associated with connective tissue disease or other systemic illness, although long-term studies are lacking.
Erroneous red blood cell parameters due to cold agglutinins were evident as increases in the MCH in 3 cases in which the operator deviated from protocol, and improper mixing of tubes run in manual mode was the likely explanation for 2 errors.
Kit dosage, id-nacl / enzyme, enzymatic test and cold agglutinins in card with 6 microtubes containing gel in saline to reverse grouping of the abo system.
His tests including full blood count, thyroid function tests, antinuclear antibody, cryoglobulin, cryofibrinogen, cold agglutinins, antiphospholipid antibodies and serum protein electrophoresis, which were performed to determine the etiology, were within normal ranges.
Blood banks employ warm saline washes to remove the circulating antibody that coats the RBCs when cross-matching blood for patients with cold agglutinins.
Mycoplasma pneumonia antibodies and cold agglutinins were found to be negative.
This should be contrasted with cold agglutinins which cause agglutination of RBCs.
clinical syndromes associated with cold agglutinins.
Formation of cold agglutinins is frequently observed during Mycoplasma pneumoniae infections.
For example, patients with Mycoplasma pneumoniae infections, the presence of cold agglutinins is useful in diagnosis.
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