cohort study

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Related to Cohort studies: panel studies

study

 [stud´e]
a careful examination of a phenomenon; see also design.
cohort study prospective study.
cross-sectional study one employing a single point of data collection for each participant or system being studied. It is used for examining phenomena expected to remain static through the period of interest. It contrasts with a longitudinal s.
electrophysiological s's (EPS) studies from within the heart of its electrical activation and response to electrical stimuli and certain drugs. In general they include intravenous and/or intra-arterial placement of one or more electrode catheters at sites in the atria, ventricles, or coronary sinus, and sometimes the pulmonary artery or aorta. They record activity or stimulate the heart at various rates and cadences and are aids in the evaluation of electrophysiologic properties such as automaticity, conduction, and refractoriness. They also initiate and terminate tachycardias, map the sequence of activation, and aid in evaluation of patients for various forms of therapy and for the response to therapy. During these studies catheter ablation procedures, such as radio frequency ablation and electrical ablation, may be performed.
flow study uroflowmetry.
longitudinal study one in which participants, processes, or systems are studied over time, with data being collected at multiple intervals. The two main types are prospective studies and retrospective studies. It contrasts with a cross-sectional s.
pilot study a smaller version of a proposed research study, conducted to refine the methodology of the later one. It should be as similar to the proposed study as possible, using similar subjects, the same setting, and the same techniques of data collection and analysis.
prospective study an epidemiologic study in which the groups of individuals (cohorts) are selected on the bases of factors that are to be examined for possible effects on some outcome. For example, the effect of exposure to a specific risk factor on the eventual development of a particular disease can be studied. The cohorts are then followed over a period of time to determine the incidence rates of the outcomes being studied as they relate to the original factors in question. Called also cohort study.



The term prospective usually implies a cohort selected in the present and followed into the future, but this method can also be applied to existing longitudinal historical data, such as insurance or medical records. A cohort is identified and classified as to exposure to the risk factor at some date in the past and followed up to the present to determine incidence rates. This is called a historical prospective study, prospective study of past data, or retrospective cohort study.
retrospective study an epidemiologic study in which participating individuals are classified as either having some outcome (cases) or lacking it (controls); the outcome may be a specific disease, and the persons' histories are examined for specific factors that might be associated with that outcome. Cases and controls are often matched with respect to certain demographic or other variables but need not be. As compared to prospective studies, retrospective studies suffer from drawbacks: certain important statistics cannot be measured, and large biases may be introduced both in the selection of controls and in the recall of past exposure to risk factors. The advantage of the retrospective study is its small scale, usually short time for completion, and its applicability to rare diseases, which would require study of very large cohorts in prospective studies. See also prospective s.
urinary flow study uroflowmetry.
voiding pressure study simultaneous measurement of bladder contraction, urinary flow, and sphincter electromyogram.

co·hort stud·y

a study using epidemiologic methods, such as a clinical trial, in which a cohort with a particular attribute (for example, smokers, recipients of a drug) is followed prospectively and compared for some outcome (for example, disease, cure) with another cohort that does not possess that attribute.
Synonym(s): follow-up study (1)

cohort study

An observational study in which a defined group of people (a cohort) is followed over time and outcomes are compared in subsets of the cohort who were exposed, not exposed, or exposed at different levels to an intervention or other factor of interest. Cohorts can be assembled in the present and followed into the future (a “concurrent cohort study”), or identified from past records and followed from that time up to the present (a “historical cohort study”). Because random allocation is not used, matching or statistical adjustment must be used to ensure that the comparison groups are as similar as possible.
References in periodicals archive ?
Although the four cohort studies have shown an increased risk of LC in HCV infected population [28, 34-36], two of them did not find the risk statistically significant [28, 35].
A systematic review investigated the association between the timing of introducing complementary (solid) foods and childhood obesity in 23 primarily cross-sectional and cohort studies (17 from the United States, Canada, and Europe) with more than 33,000 patients.
Statistical analysis: For all the included cohort studies, we computed overall RRs with 95% CIs for the highest versus lowest level of coffee consumption.
Loss to follow-up in cohort studies: bias in estimates of socioeconomic inequalities.
National birth cohort studies were pioneered in Britain by the cohort of 1946, the Medical Research Council's National Survey of Health and Development (Wadsworth, 2010).
That's because AIDS cohort studies mostly look back in time, telling you what happened years ago, not what's happening now.
In fact, the case-control and cohort studies described in "Non-Trivial Pursuits" yielded little support for the link.
This is the result of an analysis of three large cohort studies published in the Annals of Internal Medicine.
To address conflicting data on whether azathioprine increases the risk of skin cancer, the authors con ducted the analysis of 27 studies (23 cohort studies, 1 randomized study, and 3 case-control studies) published between 1996 and 2011, which evaluated skin cancer risk associated with azathioprine in people who received an organ transplant from 1963 to 2011, at a median age of 38-54 years.
Compared with diets low in soy, high dietary intake of soy protein or soy isoflavones isn't associated with any alteration in the risk of developing primary breast cancer (strength of recommendation [SOR]: B, systematic review of prospective cohort studies).
Researchers systematically reviewed prospective cohort studies with relative risk and 95% confidence intervals for breast cancer according to fish intake, n-3 PUFA intake, or tissue biomarkers.