CARAFE(redirected from Cocktail Attenuation of Rotational Ablation Flow Effects Study)
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(1) Coronary Angiography through the RAdial or FEmoral Approach. A trial comparing transradial and transfemoral approaches for coronary angiography (CA)
Primary endpoints In-hospital morbidity
Conclusion Transradial CA can be highly successful with few complications and good angiographic quality; it takes a bit longer, but permits earlier ambulation and discharge
(2) Cocktail Attenuation of Rotational Ablation Flow Effects study. A pilot study to see if the periprocedural complications of microvascular-mediated ischemia (slow flow or no reflow) and coronary vasospasm often associated with rotational ablation could be reduced, using a drug cocktail of verapamil, nitroglycerin, and heparin; 27 lesions were treated with a procedural success rate of 95%. Transient AV block is frequent, especially when treating RCA and circumflex arteries; therefore, prophylactic pacing is indicated