Sensitization to mouse and cockroach allergens
and asthma morbidity in urban minority youth: Genes-environments and admixture in Latino American (GALA-n) and Study of African-Americans, Asthma, Genes, and Environments (SAGE-II).
In contrast, cross-sectional findings in children on bedroom cockroach allergen
, all recent, have been mixed.
Adkinson Jr., "Socioeconomic status and race as risk factors for cockroach allergen
exposure and sensitization in children with asthma," Journal of Allergy and Clinical Immunology, vol.
Schal, "Cockroach allergen
biology and mitigation in the indoor environment," Annual Review of Entomology, vol.
German cockroach allergen
levels in North Carolina schools: comparison of Integrated Pest Management and conventional cockroach control.
In 2001, NIEHS researchers conducted a 6-month trial to test a new intervention method for reducing cockroach allergen
levels in low-income, urban homes.
The researchers also discovered that cockroach allergens
had a greater impact on asthma than did dust mite allergens.
From this research, Brenner and fellow researchers have developed a cockroach allergen
An estimated 20%-53% of allergic patients and 49-61% of asthmatic patients test positive in being sensitive to cockroach allergen
Exposure to cockroach allergen
in sensitized individuals can cause asthma exacerbation (Institute of Medicine [IOM], 2000) and exposure to mold among sensitized individuals is associated with asthma exacerbation (IOM, 2004).
In particular, exposure to cockroach allergen
in early life can lead to allergic airway inflammation and an increased risk of developing asthma [18,19].