Researchers are taking cues from the failed attempt to develop a cocaine vaccine
a few years ago, in which not enough antibodies were produced in about half the patients.
A potential "cocaine vaccine
" called TA-CD, which is made from succinyl norcocaine conjugated to cholera toxin, is being evaluated.
(45,46) In clinical trials, cocaine vaccine
attenuated the subjective experience and euphoria derived from smoked cocaine.
In the cocaine vaccine
study, researchers found their test vaccine prevented cocaine from entering the brains of primates.
Clinical trials for a cocaine vaccine
in development called TA-CD have reported mixed results and, at present, the vaccine is not approved for clinical therapeutic use.
Efficacy of a therapeutic cocaine vaccine
in rodent models.
'At the moment,we are the only company in the world that is advancing a cocaine vaccine
And battered drugs stock Xenova received welcome respit after it announced a new phase of trials on its cocaine vaccine
. Shares gained 1p to 12.25p.
"A cocaine vaccine
, currently under investigation by several laboratories, would be an innovative and exciting means of treating and preventing cocaine addiction," he wrote.
The cocaine vaccine
has begun human trials and the nicotine jab will follow later this year.
In the first trial of a cocaine vaccine
in humans the vaccine appeared to reduce the euphoric effects of cocaine and increased cocaine abstinence.
(1) Hopefully the cocaine vaccine
mentioned in the article will be approved, which will provide clinicians with another agent for treating dual diagnosis patients.