coagulase

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coagulase

 [ko-ag´u-lās]
a bacterial enzyme that reacts with a cofactor found in blood plasma to catalyze the formation of fibrin from fibrinogen. It is produced by most of the virulent strains of staphylococci, and by Yersinia pestis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

coagulase

(kō-ăg′yə-lās′, -lāz′)
n.
Any of various enzymes, such as rennin or thrombin, that induce coagulation.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

coagulase

An enzyme secreted by the micro-organism Staphylococcus aureus that causes clotting in blood plasma by converting prothrombin to thrombin. This ability probably contributes to the tendency of the organism to form abscesses.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Evaluation of methods for detecting oxacillin resistance in coagulase-negative staphylococci including cefoxitin disc diffusion.
Coagulase-negative staphylococci were also a more frequent (p<0.05) pathogen at JH (14.9%) than at CHB (4.8%).
Of the remaining 90 isolates, 44 were coagulase-negative staphylococci, 45 were viridans group streptococci, and 1 was Micrococcus luteus.
Coagulase-negative staphylococci were the most common isolates (45.8%), followed by Streptococcus pneumoniae (16.7%), Enterobacteriaceae (16.7%), Staphylococcus aureus (10.4%), and Pseudomonas aeruginosa (10.4%).
However, certain of the staphylococci, called coagulase-negative strains, are notoriously resistant to many antibiotics, including methicillin, a semisynthetic penicillin developed to treat penicillin-resistant bacteria.
Of the 19 units manifesting growth, 16 yielded only diphtheroids, 1 unit grew coagulase-negative staphylococci, 1 unit grew diphtheroids and micrococci, and 1 unit grew diphtheroids and coagulase-negative staphylococci.
corynebacterium species, coagulase-negative staphylococci) after [is greater than] 24 h enrichment in a thioglycolate broth.