coagulase(redirected from Coagulase-negative)
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a bacterial enzyme that reacts with a cofactor found in blood plasma to catalyze the formation of fibrin from fibrinogen. It is produced by most of the virulent strains of staphylococci, and by Yersinia pestis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Any of various enzymes, such as rennin or thrombin, that induce coagulation.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
coagulaseAn enzyme secreted by the micro-organism Staphylococcus aureus that causes clotting in blood plasma by converting prothrombin to thrombin. This ability probably contributes to the tendency of the organism to form abscesses.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005