cofactor

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cofactor

 [ko´fak-ter]
an element or principle, e.g., a coenzyme, with which another must unite in order to function.
heparin cofactor II a member of the serpin group that inhibits thrombin.

co·fac·tor

(kō'fak'ter, tōr),
1. Synonym(s): coenzyme
2. An atom or molecule essential for the action of a large molecule, for example, heme in hemoglobin, magnesium in chlorophyll. Solo metal ions are regarded as cofactors for proteins, but not as coenzymes.

cofactor

(kō′făk′tər)
n.
1. One of two or more contributing factors.
2. A substance, such as a metallic ion or coenzyme, that must be associated with an enzyme for the enzyme to function.

co·fac·tor

(kō'fak'tŏr)
1. Synonym(s): coenzyme.
2. An atom or molecule essential for the action of a large molecule; e.g., heme in hemoglobin, magnesium in chlorophyll.

cofactor

a substance that is essential for the catalytic activity of some enzymes, binding to the enzyme only during the reaction. Cofactors can be metallic ions, or nonprotein organic molecules (coenzymes) such as vitamins in the B-COMPLEX.

co·fac·tor

(kō'fak'tŏr)
An atom or molecule essential for the action of a large molecule.
References in periodicals archive ?
The reference cuvette contained all the same solutions in the same amount except for co-factor solution (0.5 ml) and phosphate buffer (2.5 ml.).
Manganese (Mn) is co-factor for manganese-superoxide dismutase, which has a role in eliminating of superoxide radicals produced by oxidative phosphorylation (6).
The response of our patients to the well intended interventions we apply depends on their stage of illness and adaptability, as well as on co-factors that determine therapeutic receptiveness and vulnerability.
Boulton sees little or no indication that tannin functions as a co-factor, or has much influence on the color of young red wines.
Vitamin B12 is a required co-factor for this enzyme but for some reason in the so-called vitamin B12-responsive forms of MMA there is insufficient co-factor available to the enzyme.
The patented NMR Solve approach allows Triad to focus on the relevant binding domains by studying the protein while a co-factor probe is bound.
Poor nutrition is a strong co-factor. An undernourished body appears to pass along the teratogenic properties of alcohol via the placenta more readily than a body that is healthy.
Infection with other STDs is an important co-factor for transmission of HIV; genital ulcer diseases in particular, such as chancroid, provide an entry point for HIV.
Had he attended the conference at the Uganda Martyrs University, he could have learned that poverty, with the inevitable consequences of poor diet, housing, sanitation and health care, is a major cause of immune deficiency without any need for HIV as a co-factor, with solutions that are too obvious to mention.
Mutual understanding is a necessary co-factor in reaching goals and objectives.
Most Americans fell short of getting the recommended 15 milligrams of daily zinc, an important mineral that serves a co-factor for hundreds of enzymes produced in the body, including digestive and antioxidant enzymes.