Cmax


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maximum concentration

The peak concentration that a drug achieves in a specified compartment after the drug has been administrated and before administration of a second dose. Cmax is the opposite of Cmin—which is the minimum (or trough) concentration that a drug achieves after dosing.

Cmax

Pharmacology The peak serum concentration of a therapeutic drug. See Pharmaco-kinetics, Tmax. Cf Trough.

Cmax

Maximum concentration of a drug achieved after dosing.
References in periodicals archive ?
Statistical comparison of pharmacokinetic parameters of wasrfarin following its single oral administration alone and alongwith caffeine has shown a non-significant difference in Cmax, Tmax, Vd and B.
Significance difference (***cP<0.001) in the values of Cmax and AUC was seen between the starch and chloroform-treated groups.
La aplicacion intramuscular provee rapida absorcion, similar a lo informado en bovinos (Apley y Upson, 1993; Shojaee Aliabadi y Lees, 2003), porcinos (Mann y Frame, 1992), caprinos (Atef et al., 2001), ovinos (McKellar et al., 1998), generando una Cmax ligeramente menor al informado en ovinos (McKellar et al., 1998) con identica dosis.
Pharmacokinetic parameters (AUC, Cmax, Tmax, t1/2, Cl, MRT and Kel) were calculated using scientific application package KineticaA(r) version 4.1.1 (Thermo Electron Corporation).
parametro grupo 1 Cmax ([micron]g/ml) 27,66 [+ o -] 4,20 Tmax (h) 1,41 [+ o -] 0,58 [lambda] ([h.sub.-1]) 0,44 [+ o -] 0,03 [T.sub.1/2] (h) 1,55 [+ o -] 0,12 AB[C.sub.0-t] ([micron]gh/ml) 105,4 [+ o -] 10,80 AB[C.sub.0-[infinito]] ([micron]g*h/ml) 110,8 [+ o -] 10,98 TMR(h) 3,19 [+ o -] 0,39 parametro grupo 2 Cmax ([micron]g/ml) 26,51 [+ o -] 6,04 n,s.
F4 presented more constant and lower TR plasma concentrations in almost all periods of time and a small Cmax and a higher MRT when compared to the free drug.
In the summer of 2014, COTA contacted ITSENCLOSURES about deploying digital signage at the new CMAX bus stops around the city of Columbus, Ohio.
1 Weighing in at 2.7 ounces, the G5 Cmax ($134.99; www.g5outdoors.com) is a full-containment drop-away arrow rest that features a launcher arm activated by either the push of a button, or simply by drawing your bow.
Mr and Mrs Davies collecting their CMAX from Day's Nick Thomas, Fordstore new car sales manager
Other models available in the new car Ford line-up includes the Ka, Fiesta, Fiesta ST, Focus, Focus ST, Mondeo, C-MAX, Grand CMAX, B-MAX, S-MAX, Galaxy and EcoSport.
He loaded his haul of a 55-inch TV, three laptops, a tablet and Wii box into the Ford CMax parked outside and was driving offat 2am when a police officer on mobile patrol challenged him in Orwell Street, Middlesbrough.