Clostridium sordellii


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Clostridium sordellii

a bacterial strain that produces multiple toxins including a lecithinase, hemolysin, and a fibrinolysin, which results in edema and potentially fatal hypotension, and necrotic infections in humans. It is especially associated with abdominal and gynecologic posttraumatic and postoperative wound infection; also causes big head in rams.

Clos·trid·i·um sor·del·li·i

(klos-trid'ē-ŭm sōr-del'ē-ī)
A bacterial species that produces multiple toxins including a lecithinase, hemolysin, and a fibrinolysin, which results in edema and potentially fatal hypotension, and necrotic infections in humans. It is especially associated with abdominal and gynecologic posttraumatic and postoperative wound infection; also causes disorder called big head in rams.

Clostridium sordellii

A species that may cause anaerobic infections in bones, joints, soft tissues, the uterus, and elsewhere.
See also: Clostridium
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This leaves the woman's body more susceptible to infections from bacteria such as Clostridium sordellii.
Miech, "Pathophysiology of Mifepristone-Induced Septic Shock Due to Clostridium sordellii," The Annals of Pharmacotherapy 39:9 (September 2005): 148388.
Rifkin et al (3) November 1977 Fecal cytotoxin was neutralized by antisera to Clostridium sordellii.
Purification and characterization of Clostridium sordellii lethal toxin and cross-reactivity with Clostridium difficile cytotoxin.
Chris Lewis said he was also sure that confirmed cases of Clostridium sordellii infection were only the tip of the iceberg and that the problem was under-diagnosed as a cause of sudden death in sheep flocks because the symptoms of infection are so similar to other conditions.
While Aldape's study looks at Clostridium sordellii infections in general, Beverly Winikoff confines her remarks to the implications of the study for chemical/RU486 abortions.
Based on our recent conversations with state and federal public health agencies, they are unable at this time to tell us how the Clostridium sordellii bacterium was introduced into the knee patient's body, and they have revealed no conclusion regarding the source of the infection in the patient," CryoLife said in the release.
There were 12 separate cultures on tissue recovered from the donor, none of these cultures were positive for Clostridium sordellii.
The FDA recommends that if physicians suspect infection in patients with this presentation, they should consider immediately initiating treatment with antibiotics that include coverage of anaerobic bacteria, such as Clostridium sordellii.
But to understand why it seems unlikely that the vaginal administration of the misoprostol could be the factor behind these deadly infections, one simply needs to understand a bit more about the Clostridium sordellii bacteria.
Clostridium sordellii is actually a quite common bacterium, found in soil and often in the human intestinal tract.