Clomid

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clomiphene citrate (clomifene (UK))

Clomid, Serophene

Pharmacologic class: Chlorotrianisene derivative

Therapeutic class: Fertility drug, ovulation stimulant

Pregnancy risk category X

Action

Binds with estrogen receptors in cytoplasm, increasing secretion of folliclestimulating hormone, luteinizing hormone, and gonadotropin in hypothalamus and pituitary gland. These actions induce ovulation.

Availability

Tablets: 50 mg

Indications and dosages

➣ Ovarian failure

Adults: 50 mg/day P.O. for 5 days starting any time in patients with no recent uterine bleeding; or 50 mg/day P.O. starting on fifth day of menstrual cycle. If ovulation doesn't occur, increase to 100 mg/day P.O. for 5 days. Start next course of therapy as early as 30 days after previous course. If patient doesn't respond after three courses, no further doses are recommended.

Off-label uses

• Male sterility (controversial)

Contraindications

• Hepatic disease

• Organic intracranial lesions

• Uncontrolled thyroid or adrenal dysfunction

• Ovarian cyst

• Abnormal uterine bleeding or bleeding of undetermined origin

• Pregnancy

Precautions

None

Administration

• Obtain pregnancy test before therapy begins.

• Be aware that patient should undergo pelvic and eye examinations before starting therapy.

Adverse reactions

CNS: nervousness, insomnia, dizziness, light-headedness

CV: vasomotor flushing

EENT: visual disturbances

GI: nausea; vomiting; abdominal discomfort, distention, and bloating

GU: breast tenderness, ovarian enlargement, multiple pregnancies, birth defects in resulting pregnancies, ovarian hyperstimulation syndrome, uterine bleeding

Interactions

None significant

Patient monitoring

• Monitor patient for bleeding and other adverse reactions.

Patient teaching

☞ Instruct patient to immediately report signs and symptoms of ovarian hyperstimulation syndrome, including nausea, vomiting, diarrhea, abdominal or pelvic pain, and swelling in hands or legs.

• Tell patient to report bleeding.

• Advise patient not to take drug if she is or may become pregnant.

• Inform patient that drug increases risk of multiple births, which heightens maternal risk.

• As appropriate, review all other significant and life-threatening adverse reactions.

Clomid

(klō′mĭd)

A trademark for the drug clomiphene.

Clomid

A brand name for CLOMIPHENE (clomifene).

Mentioned in ?

References in periodicals archive ?

For those with secondary testosterone deficiency coming from the hypothalamus-pituitary axis, which is usually the case for younger men (<50 years), HCG and Clomid MAY be superior to TRT.

A Crash Course in Erections and Testosterone

--in what ways will this upcoming IVF treatment be better than the Clomid cycles?

Psychological and emotional preparation for IVF brings numerous benefits including an improved likelihood of success--the fertile body method

Clomiphene (Clomid, Serophene) is used to induce ovulation (sometimes called controlled ovarian hyperstimulation).

Infertility

Mrs Lamb had taken Clomid, which stimulates ovulation, before falling pregnant with the sextuplets.

Heartache as sextuplet baby loses fight for life

(6.) Clomid official FDA information, side effects and use.

Association between clomiphene citrate and central retinal vein occlusion: a case report

"I had a year on [the drug] Clomid, but that didn't do anything.

'We have always hoped for a child - it would mean everything to us ...' Health Minister Edwina Hart has asked government officials to review the current Welsh policy of only offering couples one free cycle of IVF on the NHS. Health Editor Madeleine Brindley spoke to one of the women campaigning for three free cycles

a flexible range of funds to help pay for fertility treatment options like Clomid, PCOS treatment, IVF, IUI, ICSI, surgery, tubal ligation reversals, and donor eggs." (80)

The debt financing of parenthood

"Me recomendaron las pastillas para tener la menstruacion y otro medicamento que se llama Clomid para ponerme a ovular e intentar el embarazo, pero tampoco se pudo", indico.

"Tengo hambre de ser mama": cuando todo esta en contra: Cecilia Martinez no entiende como hay madres que abandonan o maltratan a sus hijos, cuando otras mujeres como ella anhelan dar a luz una nueva vida. Desbalance

Agents used were clomiphene (Clomid), clomiphene/human menopausal gonadotrophin, and follicle-stimulating hormone/human menopausal gonadotrophin.

IVF regimen linked to ovarian cancer risk

Tabela 1: Medicamentos mencionados pelos voluntarios no estudo: Nome Cientifico Nome Comercial (Brasil) Cipionato de testosterona Deposteron Citrato de Clomifeno Clomid Decanoato de Nandrolona Deca-durabolin Decanoato, Isocaproato Fenilproprionato, e Durateston Propianato (Testosterona) Enantato de Testosterona Testosviron Metrandostenolona Dianabol Oxandrolona Anavar Stanozolol Winstrol Undecilenato de Baldenone Equifort Oximetolona Hemogenin Mentelona Primobolan Cloridrato de Clembuterol Clembuterol Mesterolona Proviron

Analysis of incidence of side effects in users of anabolic steroids from the city of Bauru/Uma analise da incidencia de efeitos colaterais em usuarios de esteroides anabolizantes praticantes de musculacao da cidade de Bauru

Clomid can cause ovarian hyperstimulation syndrome, which in rare cases can be life-threatening.

The parental investment factor and the child's right to an open future

The book "Game of Shadows," by two Chronicle reporters, says Estalella received a drug schedule from Greg Anderson, Bonds' trainer, advising him to use human growth hormone, the steroids "the cream" and "the clear," and the female fertility drug Clomid.