clock

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clock

(klŏk)
n.
1. An instrument other than a watch for measuring or indicating time, especially a mechanical or electronic device having a numbered dial and moving hands or a digital display.
2. A biological clock.
v. clocked, clocking, clocks
v.tr.
To register or record with a mechanical device: clocked the winds at 60 miles per hour.

clock′er n.

CLOCK

A gene on chromosome 4q12 that encodes a ubiquitously expressed human homolog of the mouse clock gene, which forms a heterodimer with ARNTL and activates E-box element transcription of several circadian clock proteins (e.g., PER1 and PER2). CLOCK is highly expressed in the suprachiasmatic nucleus.

Molecular pathology
CLOCK-ARNTL double mutations in the PAS domains result in syngernistic desensitisation to high levels of CRY on repression of CLOCK-ARNTL transcriptional activity of PER1, disrupting circadian rhythmicity.

clock

(klok)
A device for measuring time.

biological clock

1. An internal system in organisms that influences behavior in a rhythmic manner. Functions such as growth, feeding, secretion of hormones, the rate of drug action, the wake-sleep cycle, the menstrual cycle, and reproduction coincide with certain external events such as day and night, the tides, and the seasons. Biological clocks appear to be set by environmental conditions in some animals, but if these animals are isolated from their environment they continue to function according to the usual rhythm. A gradual change in environment does produce a gradual change in the timing of the biological clock. See: circadian; maladaptation to night work; zeitgeber
2. A colloquial term for the decrease in fertility that accompanies aging, particularly as women approach the age of 35.

Patient discussion about clock

Q. How do you wake up in the morning if your narcolepsy is so severe you can't hear the alarm clock, phone ring? biggest problem is sleep paralysis, can't wake up. Late for work, everything, life is suffering because of severity. Have tried ritalin, natural supplements, hypnosis therapy, Provigal, antidepressants, nothing seems to work. Employer thinks it's an excuse, friends are irritated, I'm at my wits end. Life is spent sleeping more than awake.

A. Narcolepsy cannot yet be cured. But EDS and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment. Often the treatment regimen is modified as symptoms change. For decades, doctors have used central nervous system stimulants-amphetamines such as methylphenidate, dextroamphetamine, methamphetamine, and pemoline-to alleviate EDS and reduce the incidence of sleep attacks. For most patients these medications are generally quite effective at reducing daytime drowsiness and improving levels of alertness. However, they are associated with a wide array of undesirable side effects so their use must be carefully monitored. Common side effects include irritability and nervousness, shakiness, disturbances in heart rhythm, stomach upset, nighttime sleep disruption, and anorexia. For full article: http://www.ninds.nih.gov/disorders/narcolepsy/detail_narcolepsy.htm#120393201 Hope this helps.

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References in periodicals archive ?
Students are expected to gain appropriate bench experience, preferably with craftsmen, and work towards the Certificate in Repair, Restoration and Conservation of Clocks and Watches.
By the 1970s, the electronic quartz watch became less expensive as well as more accurate than mechanical watches, resulting in much higher sales of such clocks and watches. This has resulted in the wide distribution of inexpensive quartz watches in the United States.
She'll have too much time on her hands when she has to change the hour on all the clocks and watches at the F Hinds jewellers shop at Eagles Meadow in Wrexham.
"I suppose this will be the end of an era because there is no other place in Bedworth where clocks and watches are repaired on the premises."
On November 6, Sotheby's will sell the personal collection of watches and clocks George built over a lifetime devoted to horology: unique timepieces George made himself, together with fine and important antique clocks and watches by makers who inspired him.
All radio-controlled clocks and watches, whether they be digital or analogue, do receive an automatic one-hour time change summer and winter.