clock

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clock

(klok) a device for measuring time.
biological clock  the physiologic mechanism which governs the rhythmic occurrence of certain biochemical, physiologic, and behavioral phenomena in living organisms.

clock

(klŏk)
n.
1. An instrument other than a watch for measuring or indicating time, especially a mechanical or electronic device having a numbered dial and moving hands or a digital display.
2. A biological clock.
v. clocked, clocking, clocks
v.tr.
To register or record with a mechanical device: clocked the winds at 60 miles per hour.

clock′er n.

CLOCK

A gene on chromosome 4q12 that encodes a ubiquitously expressed human homolog of the mouse clock gene, which forms a heterodimer with ARNTL and activates E-box element transcription of several circadian clock proteins (e.g., PER1 and PER2). CLOCK is highly expressed in the suprachiasmatic nucleus.

Molecular pathology
CLOCK-ARNTL double mutations in the PAS domains result in syngernistic desensitisation to high levels of CRY on repression of CLOCK-ARNTL transcriptional activity of PER1, disrupting circadian rhythmicity.

clock

(klok)
A device for measuring time.

biological clock

1. An internal system in organisms that influences behavior in a rhythmic manner. Functions such as growth, feeding, secretion of hormones, the rate of drug action, the wake-sleep cycle, the menstrual cycle, and reproduction coincide with certain external events such as day and night, the tides, and the seasons. Biological clocks appear to be set by environmental conditions in some animals, but if these animals are isolated from their environment they continue to function according to the usual rhythm. A gradual change in environment does produce a gradual change in the timing of the biological clock. See: circadian; maladaptation to night work; zeitgeber
2. A colloquial term for the decrease in fertility that accompanies aging, particularly as women approach the age of 35.

Patient discussion about clock

Q. How do you wake up in the morning if your narcolepsy is so severe you can't hear the alarm clock, phone ring? biggest problem is sleep paralysis, can't wake up. Late for work, everything, life is suffering because of severity. Have tried ritalin, natural supplements, hypnosis therapy, Provigal, antidepressants, nothing seems to work. Employer thinks it's an excuse, friends are irritated, I'm at my wits end. Life is spent sleeping more than awake.

A. Narcolepsy cannot yet be cured. But EDS and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment. Often the treatment regimen is modified as symptoms change. For decades, doctors have used central nervous system stimulants-amphetamines such as methylphenidate, dextroamphetamine, methamphetamine, and pemoline-to alleviate EDS and reduce the incidence of sleep attacks. For most patients these medications are generally quite effective at reducing daytime drowsiness and improving levels of alertness. However, they are associated with a wide array of undesirable side effects so their use must be carefully monitored. Common side effects include irritability and nervousness, shakiness, disturbances in heart rhythm, stomach upset, nighttime sleep disruption, and anorexia. For full article: http://www.ninds.nih.gov/disorders/narcolepsy/detail_narcolepsy.htm#120393201 Hope this helps.

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References in periodicals archive ?
The four-core / eight-thread configuration that Intel has preferred since it launched Nehalem back in 2008 continues to offer an excellent overall balance of clock speed and performance, even if performance gains have materialized more slowly than we like.
The new quad-core Core i7 3840QM operates at a base clock speed of 2.
Intel's newer 90-nanometer chips will have the new naming system applied to them while existing chips will continue to be labelled by just the clock speed number.
Previously , these systems have used a low-power version of the Pentium with MMX - but Intel is now bringing the Pentium II architecture down to these systems, running at a 266MHz clock speed.
Increasing clock speeds to 1 GSPS on high-resolution DDS ICs allows our customers to generate higher output frequencies with improved dynamic performance," said Kevin Kattmann, product line director, High Speed Signal Processing Group, Analog Devices.
Operating at a fast clock speed across a wide bus, this new Network SRAM achieves a higher data throughput than competing products.
Other new features include the Rapid Execution Engine which allows certain frequently used instructions to be executed at double the core clock speed of the chip and a 400MHz system bus.
The change in process technology offers mobile users something like a 50% savings in power consumption for chips running at the same clock speed, the reason why Intel similarly introduced 0.
This is because nanotube circuits have reached a clock speed of only 52 megahertz under laboratory conditions.
AMD identifies the AMD Athlon XP processor using model numbers, as opposed to clock speed in megahertz.
Samsung's 900 Mhz GDDR3 helped NVIDIA achieve the highest memory clock speed of any commercially available graphics processor.