NSAIDs Used To Treat Lupus(*) Generic Name Brand Name Ibuprofen Motrin, Advil Naproxen Naprosyn, Aleve Sulindac Clinoril
Diclofenac Voltaren Piroxicam Feldene Ketoprofen Orudis Diflunisal Dolobid Nabumetone Relafen Etodolac Lodine Oxaprozin Daypro Indomethacin Indocin (*) Brand names included in this fact sheet are provided as examples only and their inclusion does not mean that these products are endorsed by the National Institutes of Health or any other Government agency.
In 1989, a Colorado surgeon reported that the NSAID clinoril
, commonly prescribed for arthritis, partially inhibited formation of potentially cancerous polyps in people with a rare inherited susceptibility to colon cancer.
Three other Mylan products have been approved for marketing since March: nortriptyline HC1, a generic version of Sandoz' antidepressant Pamelor; sulindac, a version of Merck & Co.'s anti-inflammatory Clinoril
; and tolmetin sodium, a version of McNeil Pharmaceutical's anti-inflammatory Tolectin.
NSAIDs, such as Motrin/Rufen, Ansaid, Naprosyn/Anaprox, Rimadyl, Voltaren, Clinoril
, Feldene, and Tolectin, should be avoided for the arthritic pain of nursing facility patients as much as possible due to their adverse GI effects in chronic usage.
Diflunisal (Dolobid [R]) thrombocytopenia, Nabumetone(Relafen [R]) leukopenia, Use of aspirin, Naproxen (Naprosyn [R]) bronchospasm, alcohol, or Piroxicam (Feldene [R]) nervousness, corticosteroids Indomethacin (Indocin [R]) tinnitus, may increase risk Sulindac (Clinoril
[R]) hearing loss.