clinical depression

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Related to Clinically depressed: depression, Major Depressive Disorder, depressive syndrome

ma·jor de·pres·sion

a mental disorder characterized by sustained depression of mood, anhedonia, sleep and appetite disturbances, and feelings of worthlessness, guilt, and hopelessness. Diagnostic criteria for a major depressive episode (DSM-IV) include a depressed mood, a marked reduction of interest or pleasure in virtually all activities, or both, lasting for at least 2 weeks. In addition, 3 or more of the following must be present: gain or loss of weight, increased or decreased sleep, increased or decreased level of psychomotor activity, fatigue, feelings of guilt or worthlessness, diminished ability to concentrate, and recurring thoughts of death or suicide. See: endogenous depression, exogenous depression, bipolar disorder.

Major depression is the most common psychiatric disorder. According to the World Health Organization, it is the leading cause of disability worldwide among people aged 5 years and older. About 10% of men and 25% of women experience major depression at some time in their lives. Approximately 20 million people a year suffer depressive illness in the U.S., where the negative impact of this disease on the economy is estimated at $16 billion annually. Risk factors for depression are drug or alcohol abuse, chronic physical illness, stressful life events, social isolation, a history of physical or sexual abuse, and a family history of depressive illness. Depression can be masked by substance abuse. In old people, it may be mistaken for senile dementia, and vice versa; the two may coexist. The disorder is believed to result from an electrochemical malfunction of the limbic system involving disturbances in the metabolism of the neurotransmitters dopamine and serotonin. In people with familial depression, the number of glial cells in the subgenual prefrontal cortex is significantly smaller than in mentally healthy people. Treatment with psychopharmaceutical agents, including tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase (MAO) inhibitors, and others, effectively controls most cases of clinical depression. Cognitive-behavioral psychotherapy has demonstrated some success in reversing depression. Refined methods of electroconvulsive shock therapy (ECT) are used in cases that do not respond to other treatment. Even in severe depression the response rate with ECT is 80% or higher. This mode of therapy has a faster onset of action, causes fewer side effects than drug therapy, and is particularly useful in elderly patients.

Farlex Partner Medical Dictionary © Farlex 2012

clinical depression

The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

major depression

A mental disorder characterised by severe depression lasting essentially without remission for at least two weeks, with symptoms that interfere with the ability to work, sleep, eat and enjoy once-pleasurable activities.
Clinical findings
Feelings of guilt, hopelessness, all-encompassing low mood accompanied by low self-esteem, persistent thoughts of death or suicide; difficulties in concentration, memory and decision-making capacity, behaviour (changes in sleep patterns, appetite, weight), physical well-being; persistent symptoms (e.g., headaches or digestive disorders) that do not respond to treatment; disabling episodic major depression can occur several times in a lifetime.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

clinical depression

Psychiatry Persistent sadness or loss of interest in activities for ≥ 2 wks in absence of external precipitants DiffDx Grief, bereavement Clinical Changed eating habits, insomnia, early morning wakening, ↓ interest in normal activities, depressed mood, fatigue, suicidal ideation. Cf Bereavement.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

Patient discussion about clinical depression

Q. I want to know what causes clinical depression? My friend is diagnosed with clinical depression. He is showing signs for the past six months. We found this when he lost interest in music which was his soul before. He lost interest in all other activities including hang out with us. We were wondering what could be the reason for the drastic change in his behavior. Very recently he stopped attending school also. We have tried to contact him but in vain. Then we got to know from his brother that he feels very low and depressed and is diagnosed with clinical depression? I want to know what causes clinical depression?

A. Any neurotransmitters imbalance in the brain can cause the mood to go down. This makes the person depressed. This can happen due to genetic impact. The social or financial difficulty can cause the disturbances in neurotransmitters, which causes depression in a person. Try to know from him whether he has any history of failures which he is hiding within him. Try to know the exact cause of depression. Depression, if left unattended, could develop in to Bipolar Disorder.

Q. What's the difference between clinical depression that needs treating, and just regularly being depressed? I'm often depressed, and i just wondered what the difference is between just being depressed, and clinical? At what point does depression become depression?

A. It depends on the duration of the episodes, the frequency and severity. Even psychiatrists have trouble to pinpoint it. They often disagree on the “borderly” cases, here is some info on the diagnose of depression:

Q. What's the difference between the depressions of the bipolar disorder and clinical depression? How can I differentiate between the two? Thanks

A. When it persists past several major bouts, it is then called "chronic" and yes, from one who has it, it can go on for many years. You keep hoping that it won't come back but it hits you and you never seem to know why. After many good days, you think its gone and life will be good again and you get hope for getting off the medicine, and then out of no where, whamm, bamm and it knocks you down again, sometimes really down there with your face in the dirt. I just keep taking my medicine, pray alot, and stay away from stressful things.

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' But deep down inside, I was lost, I was broken and truth be told, I was dead.'" Kylie was in denial when she was diagnosed as clinically depressed.
There are, after all, multiple quizzes on the internet that allow you to check if you're clinically depressed: This one may come at the very top of your search results, but it's hardly anything new.
is having openheart surgery, Nhe's losing his marbles after another of Maddie's practical jokes, Steve is clinically depressed and David is being forced to provide an alibi prepares ashes Weirdly, even though Roy is spending the day scattering Hayley's ashes, he seems to be the only one in a positive frame of mind.
"It was a like a kick in the face; as far as I was concerned, I was not clinically depressed, until I went to the first session and filled out a form, a questionnaire, asking about sleep, energy, and sadness.
But stringent safeguards must be in place to protect those who might not have the mental capacity to make such a choice, or who might be clinically depressed or experiencing pressure from friends or relatives.
Sufferers can feel tired all the time and low in mood, becoming clinically depressed and unable to do their job.
She said Mr Blacker could suffer from low moods but was not clinically depressed.
After a heart attack or even a diagnosis of heart disease, it's quite common for patients to start exhibiting some depressive symptoms, and in some cases, to become clinically depressed. Likewise, someone who may be at risk for heart disease and who becomes depressed for any number of reasons could develop cardiovascular complications, perhaps due in part to the unhealthy behaviors that are associated with depression.
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studies have shown that, when pain persists, some individuals (about 30 to 40 percent) become clinically depressed. Patients having persistent pain who are depressed not only report higher levels of pain, but also much higher levels of physical disability, psychological distress, and the use of maladaptive coping strategies, such as pain catastrophizing.
If this were the case, most of us would be clinically depressed. Depression is caused by a biological imbalance in the brain, which may be hereditary, and may leave the person vulnerable to the illness.
ADOG lover who became clinically depressed after a hit-and-run car accident has quit her high-pressure job to start a canine hydrotherapy business in Northumberland.

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