clindamycin

(redirected from Clindamycin phosphate)
Also found in: Dictionary.

clindamycin

 [klin″dah-mi´sin]
1. a semisynthetic antibiotic that is a derivative of lincomycin; used to treat gram-positive penicillin-resistant infections.
2. a semisynthetic derivative of lincomycin used systemically, topically, and vaginally as an antibacterial, primarily against gram-positive bacteria; used also as the hydrochloride and phosphate salts and as the hydrochloride salt of the ester of clindamycin and palmitic acid (clindamycin palmitate hydrochloride).
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

clindamycin

(klĭn′də-mī′sĭn)
n.
A semisynthetic antibiotic, C18H33ClN2O5S, derived from lincomycin and active against gram-positive bacteria.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

clindamycin

Infectious disease An antibiotic combined with pyrimethamine to treat and prevent toxoplasmosis, PCP and, topically, for acne vulgaris Adverse effects Diarrhea, dysgeusia. See AIDS.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

clindamycin

An antibiotic drug that penetrates well into bone to treat OSTEOMYELITIS. The drug is on the WHO official list. Brand names are Dalacin C and, for external use, Dalacin T.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
The United States Food and Drug Administration (FDA) has approved the marketing of India-based Zydus Cadila's Clindamycin Phosphate and Benzoyl Peroxide Gel, it was reported on Monday.
A New, Once-daily, Optimized, Fixed Combination of clindamycin Phosphate 1.2% and Low-concentration Benzoyl Peroxide 2.5% Gel for the Treatment of Moderate-to-Severe Acne.
% N % Benzoyl peroxide (5%) 23 19.18 9 7.50 Adapalene (0.05%) 7 5.83 4 3.33 Clindamycin (1%) 11 9.16 8 6.67 Benzoyl peroxide (2.5%) 12 10 10 8.33 Ketoconazole (2%) 7 5.83 5 4.17 Clindamycin phosphate (1%') 11 9.17 Aloevera(10%), liquid paraffin (7%), white soft paraffin (5%) DRUGS FEMALE TOTAL POLY N % N % Benzoyl peroxide (5%) 32 26.68 Adapalene (0.05%) 11 9.16 Clindamycin (1%) 19 15, 83 Benzoyl peroxide (2.5%) 22 18.33 Ketoconazole (2%) 12 10 Clindamycin phosphate (1%') 13 10.83 24 20 Aloevera(10%), liquid paraffin 120 100 (7%), white soft paraffin (5%)
An aqueous gel fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide 2.5% for the once daily treatment of moderate to severe acne vulgaris: Assessment of efficacy and safety' in 2813 patients.
An open-label, two-period, crossover study of the systemic bioavailability in healthy women of clindamycin phosphate from two vaginal cream formulations.
Erythromycin 2% gel in comparison with clindamycin phosphate 1% solution in acne vulgaris.
Clindamycin phosphate foam 1% (Evoclin Foam, Connetics Corp.) is approved for topical treatment of acne vulgaris in patients aged 12 years and older.
Healthcare company Perrigo Company plc (NYSE:PRGO)(TASE:PRGO) reported on Friday the receipt of tentative approval from the US Food and Drug Administration for the generic version of Onexton Gel (clindamycin phosphate 1.2% and benzoyl peroxide 3.75%) for the treatment of acne vulgaris.
A topical clindamycin phosphate 1.2% and benzoyl peroxide 3.75% (clindamycin-BP 3.75%) aqueous gel received approval by the US Food and Drug Administration (FDA) for acne in patients ages 12 years and older as of November 2014.
Another combination that may work is minocycline extended release (Solodyn) about 1 mg/kg daily, daily clindamycin phosphate 1.2%/tretinoin 0.025% gel, and benzoil peroxide 6% foaming cloths.
In a recent study, which included 2,813 patients, significant improvements were reported in all four domains in patients who were treated with a fixed combination of clindamycin phosphate 1.2% and benzoyl peroxide (BPO) 2.5% aqueous gel, compared with patients who were treated with individual ingredients or a vehicle for 12 weeks (Cutis 2010;86:263-7).