orofacial cleft type 5

(redirected from Cleft Lip with or without cleft Palate)
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orofacial cleft type 5

A nonsyndromic cleft lip (OMIM:608874), with or without cleft palate. Orofacial cleft type 5 is linked to defects of MSX1, which encodes a homeobox protein involved in epithelial-mesenchymal signalling that has roles in craniofacial development.
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References in periodicals archive ?
Association of single-nucleotide polymorphisms in the IRF6 gene with non-syndromic cleft lip with or without cleft palate in the Xinjiang Uyghur population.
Nonsyndromic cleft lip with or without cleft palate in arab populations: genetic analysis of 15 risk loci in a novel case-control sample recruited in Yemen.
Transforming growth factor alpha locus and nonsyndromic cleft lip with or without cleft palate: a reappraisal.
Cleft lip with or without cleft palate: associations with transforming growth factor alpha and retinoic acid receptor loci.
All the cases of the of cleft lip with or without cleft palate and isolated cleft palate attending OPD of Govt.
Out of 82 patients (of cleft lip with or without cleft palate and isolated cleft palate) 40 are males while 42 are females.
0.6: 1 It means that cleft lip with or without cleft palate is more common in males and isolated cleft palate is more common in females and this is in accordance with the findings of Neel (1958); (13) Theodore.
In cleft lip with or without cleft palate patients, 12% patient had positive family history.
In the present study, the frequency distribution of loops (particularly ulnar loops) is increased in cleft lip with or without cleft palate and isolated cleft palate cases as compared to the control group C.
In our study also there is an increase in frequency of loops in the fingers in both cleft lip with or without cleft palate and isolated cleft palate cases.
infants are born with an orofacial cleft (1), which includes cleft palate and cleft lip with or without cleft palate. Because of their prevalence and substantial costs to families and the health-care system (2-4), craniofacial defects significantly affect public health.
nbdps.org) has indicated an increased risk for cleft lip with or without cleft palate associated with maternal diabetes (5) and smoking (6) and an increased risk for craniosynostosis associated with maternal thyroid disease or its treatment during pregnancy (7).