Borderline clear cell tumor
of the ovary is defined as a tumor that is composed of glands or cysts lined by bland cuboidal to flattened cells with clear or eosinophilic cytoplasm and atypia but without stromal invasion .
Nogales, "Metastasis from papillary renal cell carcinoma masquerading as primary ovarian clear cell tumor
," Pathology Research and Practice, vol.
(4) The smooth muscle component is derived from the perivascular epithelioid cell (PEC), and hence, AML is one of a number of tumors classified under the general term PEComa, a group that includes clear cell tumor
Endoscopic ultrasonography (EUS) revealed a mass in the head of pancreas and fine needle aspiration (FNA) showed a clear cell tumor
suggestive of renal cell carcinoma.
The resection of the tumor showed a clear cell tumor
embedded in a rich capillary network, similar to previously described cases in this review.
The index case was such an example, where a small biopsy of an epithelioid clear cell tumor
, clinically thought to be a metastatic carcinoma, was initially presumed to be an RCC based on the CD10 positivity.
The clear cell tumor
component grew in solid, papillary, tubular, and acinar patterns with focal melanin pigmentation.
Benign lung tumors in the differential diagnosis include clear cell tumor
, pulmonary hamartoma, and hemangioma.
Any of these tumors may have clear cell change, in some cases being so abundant as to mimic metastatic renal cell carcinoma or other clear cell tumors
. The subtypes of acrospiroma are explored below.
Smoking was tied to a higher risk of mucinous tumors (RR per 20 pack-years, 1.20; 95% CI, 1.041.39) but was associated with a lower risk of clear cell tumors
(RR, 0.68; 95% CI, 0.53-0.89).
Women who had given birth to one child had a 20 percent lower overall risk of ovarian cancer and a 40 percent lower risk of endometrioid and clear cell tumors
(two specific types of ovarian cancer) than women with no children.
Rather than metaplasia of the surface epithelium, endometrioid and clear cell tumors
may result from retrograde menstruation, with the fallopian tube acting as a conduit for cells to gain access to the peritoneal cavity and the ovarian surface.