claudin


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claudin

(klaw'din),
A membrane protein, juxtaposed strands of which form tight junctions between epithelial cells.
See also: tight junction, zonula occludens.
[L. claudo, to close up, + -in]

claudin

Any of more than 20 small (less than 22 kD) transmembrane proteins which are part of the proteins in the tight junctions in endothelial and epithelial cells, and are critical for forming the paracellular space through which molecules flow between epithelial cells.
References in periodicals archive ?
Claudins are tetraspan membrane proteins essential components of the paracelular barriers found in tight junctions of all epithelia and endothelia which contain a longer intracellular C-terminus through which the majority of human claudins interact with PDZ domains of various proteins (Gunzel & Yu, 2013).
Una aguda critica de izquierda al informe Suslov en CLAUDIN, La crisis, pp.
After 21 days, the expressions of albumin, AFP, CK18, CK19, G6P, claudin, HNF4, and CYP2B6 mRNA were evaluated in the cells cultured on the 2D collagen films and in the 3D collagen scaffolds and compared to the control group.
In the crystal lattice, the claudin protomers form a linear polymer structure.
cotransporter (NKCC1), apical cystic fibrosis transmembrane conductance regulator (CFTR), and cation leaky tight junctions between neighboring cells, which are structurally and functionally defined by various claudin isoforms.
Brobeck seeks the origins of Claudin de Sermisy's syntactic motet style in the music of Antoine de Fevin.
Federico Engels, citado por Fernando CLAUDIN (1975).
Carmen Claudin, bien lo explica en su "Por que teme Putin al Maidan": ".
Mutations in the tight-junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure.
Specific topics include charge-selective claudin channels, dynamic properties of the tight junction barrier, the regulation of tight junction in human normal pancreatic duct epithelial cells and cancer cells, diverse types of junctions containing tight junction proteins in stratified mammalian epithelia, and the involvement of claudins in zebrafish brain ventricle morphogenesis.