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The principal constituent of a polyhedral protein lattice that coats eukaryotic cell membranes (vesicles) and coated pits and appears to be involved in protein secretion and membrane trafficking. This protein also occurs in synaptic vesicles.
[L. clathri, lattice]
Farlex Partner Medical Dictionary © Farlex 2012


a protein of eukaryotic cells occurring in indentations of the plasma membrane. These indentations are known as clathrin-coated pits; see RECEPTOR-MEDIATED ENDOCYTOSIS.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
This receptor is internalized in clathrin-coated vesicles by its interaction with AP2.
Kawashima, "Identification and Characterization of Membrane-Bound Calpains in Clathrin-Coated Vesicles from Bovine Brain," European Journal of Biochemistry, vol.
Nef sequesters the vesicular traffic of the cells through the modulation of some adapter and accessory proteins involved in the formation of clathrin-coated vesicles [55, 56].
Dab2 also has numerous functions outside of CME, and so the extent of its association with clathrin-coated vesicles varies between cell types [40, 41].

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