Clara cell


Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia, Wikipedia.

Cla·ra cell

(klahr'ah),
a rounded, club-shaped, nonciliated cell protruding between ciliated cells in bronchiolar epithelium; believed to be secretory in function.

Clara cell

A cuboidal epithelial cell found in the lining of the terminal and the respiratory bronchioles of the lungs. Clara cells are nonciliated, and they secrete surfactant, like the type II alveolar epithelial cells found deeper in the bronchial tree.
See also: cell

Clara cell

(klăr′ă, klah′ră)
[Max Clara, Austrian anatomist, 1899–1937]
One of the secreting cells in the surface epithelium of the bronchioles. These cells, along with goblet cells, provide secretions for the respiratory tract. The secretion is a mucus-poor protein that coats the epithelium.

Clara,

Max, Austrian anatomist, 1899–.
Clara cell - a rounded, club-shaped, nonciliated cell protruding between ciliated cells in bronchiolar epithelium; believed to be secretory in function. Synonym(s): bronchiolar exocrine cell
Clara hematoxylin
References in periodicals archive ?
Delgado-Franco et al., "Clara cell protein expression in human neonates during respiratory distress syndrome," Cellular Physiology and Biochemistry, vol.
Clara cells and AEC II cells do not match the definition of stem cells, due to not only their large number but also their specific secretory function.
for identity with the Clara cell protein and occurrence in
CCSP protein in distal airways of late control (E) and late BPA exposed (F) was expressed in cells resembling Clara cells (arrows).
Altered lung gene expression in CCSP-null mice suggests immunoregulatory roles for Clara cells. Am J Physiol Lung Cell Mol Physiol.
There are three major epithelial cell types in the airways: ciliated cells, Clara cells, and goblet cells.
Whitsett, "Clara cell secretory protein decreases lung inflammation after acute virus infection," The American Journal of Physiology: Lung Cellular and Molecular Physiology, vol.
Sections were assessed for surfactant protein A (sc-7699), Clara cell protein 10 (sc-9772), cytokeratin 10 (sc-58720), and cytokeratin 14 (sc-53253) using antibodies from Santa Cruz Biotechnology (Santa Cruz, CA, USA) and cytokeratin 19 (CRC946) from Cell Marque (Rocklin, CA, USA).
Expression of surfactant associated protein-A and Clara cell 10 kilodalton mRNA in neoplastic and non-neoplastic human lung tissue as detected by in situ hybridization.
Shortly before and 6 hr after exposure, blood samples were taken and analyzed for Clara cell protein 16, blood cell count, and markers of coagulation and inflammation.
(21,22) Thyroid transcription factor-1 is a potent transcriptional activator of genes specific to the thyroid (thyroglobulin, thyroid peroxidase, thyrotropin receptor) and lung (surfactant proteins A, B, C, and D, and Clara cell secretory protein) and plays a role in the organogenesis of the thyroid gland and the lungs.