2006) observed that infection with Citrobacter rodentium
induced anxiety-like behaviors via vagal sensory regulation.
Attaching and effacing pathogens include enterohemorrhagic and enteropathogenic Escherichia coli (EHEC and EPEC, respectively) and Citrobacter rodentium
Consequences of Citrobacter rodentium
infection on enteroendocrine cells and the enteric nervous system in the mouse colon.
The disruption of gut microbiota that facilitates gut colonization has been demonstrated in murine models infected with Citrobacter rodentium
and Salmonella enterica serovar Typhimurium (13).
translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in mice.
Intimin-specific immune responses prevent bacterial colonization by the attaching-effacing pathogen Citrobacter rodentium
Other pathogens displaying similar histopathologic features include Hafnia alvei, Citrobacter rodentium