Churg-Strauss syndrome


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Churg-Strauss syndrome

 [cherg strous]
a form of systemic necrotizing vasculitis in which there is prominent lung involvement with severe asthma, eosinophilia, and granulomatous reactions. If present, skin lesions consist of tender subcutaneous nodules and bruiselike spots. Called also allergic granulomatosis, allergic granulomatous angiitis, and Churg-Strauss vasculitis.

Churg-·Strauss syn·drome

(chŭrg strows),
asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas.

Churg-Strauss syndrome

An autoimmune vasculitis of small to medium blood vessels with hypereosinophilia arising in a background of asthma and allergic rhinitis, which may be accompanied by tissue eosinophilia, peripheral neuropathy, gastrointestinal necrosis, cardiac lesions, and renal disease. Skin lesions are common in the form of purpura, erythema, urticaria and nodules arising on the scalp and/or extremities.

Churg-Strauss syndrome

Allergic granulomatosus & angiitis Internal medicine A small vessel vasculitis characterized by eosinophil-rich and granulomatous inflammation of the respiratory tract, formation of ANCA and necrotizing vasculitis of small-to-medium-sized vessels associated with asthma, edema. See Small vessel vasculitis, Systemic vasculitis.

Churg-Strauss syndrome

A rare form of blood vessel inflammation (vasculitis) that is almost invariably accompanied by severe ASTHMA. The cause is unknown and although the condition responds well to treatment with steroids or immunosuppressive drugs, the asthma usually persists. The syndrome is distinct from other vasculitides. There are suspicions that it may possibly be caused by certain drugs used to treat asthma, especially antileukotriene drugs.

Churg,

Jacob, Polish-born U.S. pathologist, 1910–.
Churg-Strauss syndrome - asthma, fever, eosinophilia, and varied symptoms and signs of vasculitis, primarily affecting small arteries, with vascular and extravascular granulomas. Synonym(s): allergic granulomatosis; allergic granulomatous angiitis; Strauss-Churg-Zak syndrome

Strauss,

Lotte, U.S. pathologist, 1913-1985.
Churg-Strauss syndrome - see under Churg
Strauss-Churg-Zak syndrome - Synonym(s): Churg-Strauss syndrome

Zak,

Frederick G., U.S. physician.
Strauss-Churg-Zak syndrome - Synonym(s): Churg-Strauss syndrome
References in periodicals archive ?
Kobayashi et al., "Churg-strauss syndrome versus chronic eosinophilic pneumonia on high-resolution computed tomographic findings," Journal of Computer Assisted Tomography, vol.
Churg-Strauss syndrome associated with acalculous cholecystitis and liver involvement.
Faure et al., "Hepatitis C virus infection with and without cryoglobulinemia as a case of Churg-Strauss syndrome," Journal of Rheumatology, vol.
Wang et al., "Acase report of Churg-Strauss syndrome presenting with cardiogenic shocktreated with extracorporeal membrane oxygenation," Medicine, vol.
Neurolaryngeal involvement in Churg-Strauss syndrome. Eur Arch Otorhinolaryngol.
Toumelin et al., "Long-term followup of polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: analysis of four prospective trials including 278 patients," Arthritis and Rheumatism, vol.
When his loving wife Ethel, who he refers to as Effie, was diagnosed with Churg-Strauss syndrome, an autoimmune condition that causes the inflammation of small and medium-sized blood vessels in persons with a history of airway allergic hypersensitivity, Alan thought it would be best for them both to move to Bahrain to be near their daughter Linda, 57, an executive assistant to the co-chief executive officer and chief financial officer of Investcorp, and granddaughters.
Subsets include eosinophilic gastrointestinal disorders (affects esophagus, stomach, or intestines); eosinophilic granulomatosis with polyangiitis, aka Churg-Strauss Syndrome, (affects lungs, sinuses, heart, and various organ systems); and hypereosinophilic syndrome (affects blood and organs).
Examples of autoimmunity diseases include celiac disease, diabetes mellitus type 1, sarcoidosis, systemic lupus erythematosus (SLE), Sj6gren's syndrome, Churg-Strauss syndrome, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's disease, rheumatoid arthritis (RA), polymyositis (PM), dermatomyositis (DM), pemphigus vulgaris, cicatricial pemphigoid, multiple sclerosis, inflammatory bowel diseases (e.g., ulcerative colitis and Crohn's disease), pernicious anemia, scleroderma, and primary biliary cirrhosis.
Patients with allergic disorders, pemphigus, parasite infestations, Castleman's disease, Churg-Strauss syndrome, or IgG4-RD were excluded.