bacterial artificial chromosome

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bacterial artificial chromosome

n. Abbr. BAC
A large DNA sequence that is artificially inserted into a bacterial genome for replication or expression.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

bacterial artificial chromosome (BAC)

CLONING VECTOR based on the F PLASMID of ESCHERICHIA COLI, with the capacity to accept DNA inserts generally 100–300kb in size. Often used in the CLONE CONTIG SEQUENCING METHOD to obtain sequence CONTIGS in a genome sequencing project. See HUMAN GENOME PROJECT.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005