colorimetric in situ hybridization

(redirected from Chromogenic in Situ Hybridization)
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colorimetric in situ hybridization

automated paraffin-based method used to detect plasma-cell and B-cell immunoglobulin light-chain restriction in bone marrow biopsies, among others. Also analogous to fluorescence in situ hybridization for detection of HER-2 gene amplification.
References in periodicals archive ?
Chromogenic in situ hybridization is easily integrated into clinical laboratory testing, with lower cost implications and a faster turnaround time for results.
Chromogenic in situ hybridization was performed on 52 uveal melanoma cases in this study (see Table 1).
Chromogenic in situ hybridization for the detection of HER-2/neu gene amplification in breast cancer with an emphasis on tumors with borderline and low-level amplification: does it measure up to fluorescence in situ hybridization?
Chromogenic in situ hybridization to detect EGFR gene number in cell blocks from fine needle aspirates of non-small cell lung carcinomas and lung metastases from colo-rectal cancer.
Chromogenic in situ hybridization to detect HER-2/neu gene amplification in histological and ThinPrep-processed breast cancer fine-needle aspirates: a sensitive and practical method in the trastuzumab era.
Since the dual ISH assay uses 2-color chromogenic in situ hybridization to determine gene status, these slides, unlike the FISH slides, can be archived and do not fade over time.
Establishing a protocol for immunocytochemical staining and chromogenic in situ hybridization of Giemsa and Diff-Quick prestained cytological smears.
Absence of chromosome 17 polysomy in breast cancer: analysis by CEP17 chromogenic in situ hybridization and multiplex ligation-dependent probe amplification.
43) Currently HER2 testing is carried out by several methods: IHC, FISH, chromogenic in situ hybridization (CISH), and silver-enhanced in situ hybridization (SISH).
Chromogenic in situ hybridization uses chromogens for signal identification by means of indirect labeling.
Chromogenic in situ hybridization is less time consuming, is more easily read by pathologists due to similarities with IHC, and requires only brightfield microscopy.