chromatin

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Related to Chromatin structure: nucleosome

chromatin

 [kro´mah-tin]
the substance of the chromosomes, composed of DNA and basic proteins (histones), the material in the nucleus that stains with basic dyes.
sex chromatin the persistent mass of the material of the inactivated X chromosome in cells of normal females; called also Barr body.

chro·ma·tin

(krō'ma-tin),
The genetic material of the nucleus consisting of deoxyribonucleoprotein that occurs in two forms during the phase between mitotic divisions: as heterochromatin, seen as condensed, readily stainable clumps; as euchromatin, dispersed lightly staining or nonstaining material. During mitotic division the chromatin condenses into chromosomes.
[G. chrōma, color]

chromatin

(krō′mə-tĭn)
n.
A complex of nucleic acids and proteins, primarily histones, in the cell nucleus that stains readily with basic dyes and condenses to form chromosomes during cell division.

chro′ma·tin′ic adj.

chromatin

The threadlike stainable material seen in nuclei during interphase, which corresponds to chromosomes (nucleic acids/DNA, associated histones, and other proteins bundled into nucleosomes) in the eukaryotic nucleus.

chromatin

Genetics The stainable material of interphase nuclei corresponding to chromosomes; chromatin consists of nucleic acids–DNA and associated histone protein, which are packed into nucleosomes; euchromatin is loosely packed and accessible to RNA polymerases. See Salt & pepper chromatin. Cf Heterochromatin.

chro·ma·tin

(krō'mă-tin)
The genetic material of the nucleus, consisting of deoxyribonucleoprotein. During mitotic division, the chromatin condenses into chromosomes.
[G. chrōma, color]

chromatin

DNA. The elongated, fine-stranded complex of roughly equal quantities of DNA and the protein histone, from which chromosomes are made by condensing into a coil. The individual chromosomes cannot be distinguished in a chromatin strand.

chromatin

that part of the cell nucleus which becomes deeply stained with basic dyes. This is now known to be chromosomal material consisting of DNA together with HISTONE and nonhistone proteins.

chro·ma·tin

(krō'mă-tin)
The genetic ma terial of the nucleus, consisting of deoxy ribonucleoprotein. During mitotic division, the chromatin condenses into chromosomes.
[G. chrōma, color]
References in periodicals archive ?
Consequently, an open chromatin structure does not imply the absence of repressed genes and, in contrast, closed chromatin does not imply their presence.
This probably causes the change in chromatin structure from heterochromatin to euchromatin.
A complex combination of these histone modifications is thought to regulate chromatin structure and gene transcription.
Notably, both of H3K9 methylation and HDAC-mediated deacetylation are induced on nucleosome histones near cyclin E promoter region after pRB-mediated E2F inactivation [15], suggesting that pRB has the ability to alter local chromatin structure via Suv39h1, HP1, and HDAC.
In most cells, more than 80% of all genes are "silenced" due to the surrounding chromatin structure. Thus, a major challenge of recombinant protein expression is the successful integration of these recombinant genes into areas in the chromatin where transcription is not silenced.
Recent research suggests that ncRNA may have layers of information or signals that control chromatin structure and epigenetic memory.
Tapscott, "Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure," Proceedings of the National Academy of Sciences of the United States of America, vol.
Histonc hyper-acetylation induces a loose chromatin structure and facilitates topoisomerase-induced DNA strand breaks.
Histone post-translational modifications play an important role in modulating dynamic changes in chromatin structure and gene expression.
(1) Once the identity of each new cell type has been established by lineage-specific transcription factors, this identity is maintained through unique alterations in the way in which the DNA encoding each gene becomes packaged around certain proteins (i.e., the histones) within the chromatin structure of the nucleus (Hemberger et al.
The major functional categories these genes are involved in have been identified: cell receptor signaling, chromatin structure and transcription, control of cell death, cell cycle, Wnt/beta-catenin signaling, and lipid signaling.
Bio-Rad Laboratories' EpiQ chromatin analysis kit is a real-time PCR assay for the rapid quantitative assessment of chromatin structure. Complementing existing epigenetic assays such as DNA methylation and chromatin immunoprecipitation, the kit helps scientists quantify the impact of epigenetic events on gene expression regulation through chromatin state changes.