Nowycky, "Calcium dependence of large dense-cored vesicle exocytosis evoked by calcium influx in bovine adrenal chromaffin cells
," Journal of Neuroscience, vol.
Undiagnosed chromaffin cell
tumors can present with life-threatening complications for both the mother and fetus.
Finally, in medullar region, large chromaffin cells
and numerous blood vessels, similar to that described in Cavia porcellus were found (Kmiec and Kaczmarczyk, 2004).
Nussdorfer, "Paracrine control of adrenal cortical function by medullary chromaffin cells
," Pharmacological Reviews, vol.
Yoshizumi, "Effects of bioflavonoids on exocytotic releasee of catecholamines from digitonin-permeabilized chromaffin cells
: a comparison with the effects of other protein kinase C inhibitors," Neurochemistry International, vol.
A phaeochromocytoma is a rare neuro-endocrine tumour of the paraganglionic chromaffin cells
affecting 2-8 persons per million per year.[1-6] Although usually benign, around 10% are found to be malignant.[1,2,7] They can arise in the adrenal medulla and also, in around 10% of cases, in the extra-adrenal paraganglionic cells.[1,3-5] These extra-adrenal tumours are known as paragangliomas.
Cathecolamines (epinephrine and norepinephrine) and more than thirty biologically active peptides (neuropeptide Y, dopamine, chromogranins A, B, C, methionine, calcitonin gene-related peptide, leucine, enkephalin, substance P, synaptophysine, endotelins, adrenomedullin, interleukin-1) are stored in coated granules within the chromaffin cells
and are delivered through cellular depolarization and exocytosis via adrenal vein into the circulating blood (Colomer 2009).
PCCs are rare catecholamine-producing tumours thought to arise from chromaffin cells
in the adrenal medulla.
Rapid sprouting of filopodia in nerve terminals of chromaffin cells
, PC12 cells, and dorsal root neurons induced by electrical stimulation.
The PCI 2 cell line is derived from an induced pheochromocytoma and, when grown in a serum-supplemented medium, PCI 2 cells exhibit many features of their normal counterparts, adrenal chromaffin cells
(Greene and Tischler 1976).
Modifications of intracellular [Ca.sup.2+] signalling during nerve growth factor-induced neuronal differentiation of rat adrenal chromaffin cells
. Eur J Neurosci 2001; 13(8): 487-00.