choriogonadotropin


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choriogonadotropin

 [ko″re-o-gon´ah-do-tro″pin]
choriogonadotropin alfa human chorionic gonadotropin produced by recombinant technology, used to induce ovulation and pregnancy in certain infertile, anovulatory women, and to increase the numbers of oocytes for patients attempting conception using assisted reproductive technologies such as gamete intrafallopian transfer (GIFT) or in vitro fertilization; administered subcutaneously.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cho·ri·on·ic go·nad·o·tro·pin (CG),

a glycoprotein with a carbohydrate fraction composed of d-galactose and hexosamine, extracted from the urine of pregnant women and produced by the placental trophoblastic cells; its most important role appears to be stimulation, during the first trimester, of ovarian secretion of the estrogen and progesterone required for the integrity of conceptus; it appears to play no significant role in the last two trimesters of pregnancy, as the estrogen and progesterone are then formed by the placenta. CG has luteinizing hormone activity and exerts its actions through luteinizing hormone receptors.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Testicular cancer secretes intact human choriogonadotropin (hCG) and its free [beta]-subunit: evidence that hCG (+ hCG- [beta]) assays are the most reliable in diagnosis and follow-up.
Simple enzyme immunoassay for the simultaneous measurement of whole choriogonadotropin molecules and free beta-subunits in sera of women with abnormal pregnancies or tumors of the reproductive system.
[3] Nonstandard abbreviations: CHIT, chitosan; SPCE, screen-printed carbon electrode; TBO, toluidine blue 0; GDI, glutaric dialdehyde; HRP, horseradish peroxidase; ECL, electrochemiluminescence; CEA, carcinoembryonic antigen; [alpha]-AFP, a-fetoprotein; CA 125, carcinoma antigen 125; [beta]-hCG, /3-human choriogonadotropin.
Four rapid serum-urine combination assays of choriogonadotropin (hCG) compared and assessed for their utility in quantitative determinations of hCG.
Pathophysiological importance of various molecular forms of human choriogonadotropin [Review].
Elevation of free [beta] subunit of human choriogonadotropin and core [beta] fragment of human choriogonadotropin in serum and urine of patients with malignant pancreatic and biliary disease.
Pregnancy serum contains the 0-core fragment of human choriogonadotropin. J Clin Endocrinol Metab 1990;70:783-7.
Elevation of free [beta] subunit of human choriogonadotropin and core R fragment of human choriogonadotropin in serum and urine of patients with malignant pancreatic and biliary disease.
The concentration of human choriogonadotropin measured in the samples from women who claimed never to have been pregnant was in all cases <5 IU/L and therefore negative.