Taking into consideration the above-mentioned relations, the present quantitative evaluation of both CS, as an early marker of aggrecan degradation, and chondroitin sulfate 846 epitope (CS846), as a biomarker of aggrecan synthesis, is an attempt at answering the question whether the therapy used in JIA patients, whose purpose is to reduce the inflammatory and immunological parameters of the disease activity, simultaneously contributes to the normalization of biochemical changes in aggrecan and thus inhibits the dysfunction of articular cartilage.
The tested compound was quantitatively measured using an Aggrecan Chondroitin Sulfate 846 Epitope Elisa test kit provided by IBEX Pharmaceuticals Inc.
Hughes, "Chondroitin sulfate sulfation motifs as putative biomarkers for isolation of articular cartilage progenitor cells," Journal of Histochemistry and Cytochemistry, vol.
2) Determination of the domain structure of chondroitin sulfate E octasaccharides binding to type V collagen.
In the case of when chondroitin sulfate chains of proteoglycans are incubated with testicular hyaluronidase which is a glycosidase, short oligosaccharides coupling to the linkage region of proteoglycans remain.
(1956) Transglycosylation during the mixed digestion of hyaluronic acid and chondroitin sulfate by testicular hyaluronidase.
Joint Health Ingredients: Chondroitin sulfate marine; chondroitin sulfate marine LMW Ca, Na; D-glucosamine sulfate; shark cartilage; lactoferrin
Joint Health Ingredients: BioCell Collagen II[R], hyaluronic acid, collagen type II, chondroitin sulfate
Martins Press, Griffin, 224pp., $22.95) has persuaded many people to try the authors' recommendations, including the use of two nutritional supplements called glucosamine sulfate and chondroitin sulfate. Not surprisingly, sales of these supplements have soared, and although they used to be available only in health food stores, more recently they have appeared on the shelf of every drug store, and are widely promoted.
Chondroitin sulfate is one of a group of compounds called glycosaminoglycans, and is a complex carbohydrate derivative found in cartilage.
Joint Health Products: SAMe, chondroitin sulfate, MSM, omega 3 and 6
Joint Health Products: Glucosamine sulfate, glucosamine hydrochloride, chondroitin sulfate, methylsul-fonylmethane (MSM)