chondrocytes


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chondrocytes

Cells that secrete the non-cellular matrix of cartilage and become trapped in minute spaces within it.
References in periodicals archive ?
Melissa Compton, who has recently finished her challenge of swimming the River Severn to raise money for Versus Arthritis, had Autologous Chondrocyte Implantation (ACI) treatment at The Robert Jones and Agnes Hunt Orthopaedic Hospital (RJAH) three years ago, after suffering with arthritis since her mid-twenties.
Laser-scanning confocal microscopy images showing the viability of chondrocytes cultured in vitro with 0 (control), 0.125, 0.25, and 0.5 mg/mL JJYMD-C for 2, 4, and 6 days.
The effects produced by MIA are strongly related to its concentration with cell count decreasing in the central regions of the cartilage suggesting that the chondrocytes in the central region are more sensitive to MIA7.
The marine collagen scaffolds were seeded with nasal chondrocytes from rats and humans and implanted in an orthotopic rat model.
The MIT team suspected that this was because the drugs were cleared from the joint before they could reach the deep layer of chondrocytes that they were intended to target.
OA chondrocytes were obtained from 10 OA patients (aged 58-75 years) who had undergone total knee replacement at the Department of Orthopedic Surgery, Huadong Hospital, Fudan University.
Chondrocyte and cartilage replacement represent potential new therapies for treatment of OA and a broad range of degenerative and debilitating diseases that could dramatically reduce the need for mechanical devices.
These changes included disarranged chondrocytes with degeneration or necrosis, ulcerations in the deep cartilage layer, and fibroplasia at the bottom of the ulcers (Figure 1a).
Although the initial situation is different with MACI, as the chondrocytes are pre-seeded in the collagen membrane, it was observed that the seeded chondrocytes migrate from the patch into the fibrin glue in the defect depth during the first days after implantation (Jones et al., 2008).
They have demonstrated that human urine-derived stem cells (hUSCs) can be differentiated into chondrocytes in vitro and enhanced wounded rabbit knee joint healing in vivo.