cholic acid

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cholic acid

 [ko´lik, kol´ik]
one of the primary bile acids, usually found conjugated with glycine or taurine; it facilitates fat absorption and cholesterol excretion.

cho·lic ac·id

(kō'lik as'id),
A family of steroids comprising the bile acids (or salts), generally in conjugated form (for example, glycocholic and taurocholic acids). Chemically, cholic acids are cholan-24-oic (cholanic) acids (the terminal C24 of cholane becoming a -COOH group); biologically, cholic acids are derived from cholesterol (a cholestane derivative) and display varying degrees of oxidation (OH groups) and orientation at positions 3, 7, and 12. It is these oxidations and orientations that distinguish the several cholic acid; for example, cholic acid is 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid, and deoxycholic acid is 3α,12α-dihydroxy-5β-cholanic acid. Cholic acid is a naturally occurring detergent in mammals that aids in the digestion of fats.

cholic acid

(kō′lĭk)
n.
An abundant crystalline bile acid, C24H40O5, derived from cholesterol.

cho·lic ac·id

(kō'lik as'id)
A family of steroids comprising the bile acids (or salts), generally in conjugated form (e.g., glycocholic and taurocholic acids); cholic acids are derived from cholesterol.

cholic acid

a crystalline BILE acid.
References in periodicals archive ?
The UV-visible absorption spectrum of cholic acid showed absorption band with maxima at 239 nm, while all metal cholates gave single band with maxima at 259.2 nm.
When copper, cobalt, and zinc cholate reacted with hot 1:1 HCl, the metal-cholic acid bond break ending with cholic acid and metal chloride mixture, which appeared as a faint precipitates, but chromium and nickel cholate did not respond to this reagent.
It worth mentioning that the only similar work found in literature is that of Kishu [6], who prepared a set of what they call organometallic complexes of cholic acid. Organometallic compounds should contain carbon-metal bond (C-M bond), metal cholates did not contain such bonds.
"Antibacterial activity of cholanic acids stereoisomers compared to cholic acid on the test cultures of microorganisms.", Annals of Mechnikov Institute, 2: 35-38.
Schillen et al., "Amino acid-bile acid based molecules: extremely narrow surfactant nanotubes formed by a phenylalanine-substituted cholic acid," Chemical Communications, vol.