cholesteryl ester transfer protein

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cholesteryl ester transfer protein (CETP)

a plasma glycoprotein that plays a role in the movement of cholesterol from the peripheral tissue to the liver by mediating the transfer of cholesteryl esters from HDL cholesterol to apolipoprotein B-containing proteins, which are then metabolized to lipoproteins that are removed from the circulation by receptors in the liver. Deficiency of this protein, an autosomal-dominant trait, results in markedly higher plasma levels of HDL cholesterol and apolipoprotein A-I. Also called lipid transfer p. I.

cholesteryl ester transfer protein

Abbreviation: CETP
A protein that circulates in plasma and facilitates the chemical transfer of cholesteryl esters from high-density lipoproteins to other lipoproteins.
See also: protein
References in periodicals archive ?
Anacetrapib belongs to a new class of medications known as cholesterylester transfer protein (CETP) inhibitors, which block the ability of an enzyme (CETP) to transfer cholesterol particles from HDL to LDL.
Increased high-density lipoprotein levels caused by a common cholesterylester transfer protein gene mutation.
For example, men with the B2/B2 variant of the cholesterylester transfer protein (CETP) gene (see Table 2) have higher high-density lipoprotein cholesterol (HDL-C) concentrations that protect from CAD risk (Brousseau et al.