(7) Detroit's Parke, Davis went on from its nineteenth-century beginnings to develop such important drugs as Dilantin in 1938 and Chloromycetin
in 1949; although in 1970 it became a division of the New Jersey-based pharmaceutical giant, Warner-Lambert, it continues to be a significant element in the economies of the several Michigan cities where its plants are located.
The scales of skin scraped from lesions and epilated hair were inoculated on Sabouraud Dextrose Agar (SDA) with Chloromycetin
and Cycloheximide by spot inoculation method for isolation of fungi.
(16-18) It was originally made available to all optometrists as PoMs (eg, PoM Chloromycetin
eye drops and ointments, generic PoM Chloramphenicol eye drops and ointments, and the PoM Minims Chloramphenicol; British National Formulary, 2010).
The diagnostic criteria for occupational BP, according to the Ministry of Health, China, include a) total white blood cell count < 4,000/[micro]L or white blood cell count between 4,000 and 4,500/[micro]L and platelet count < 80,000/[micro]L, with repeated confirmation of this count in a few months in a peripheral blood examination; b) the individual with documented benzene exposure has been employed for at least 6 months in the factory; and c) exclusion of other causes of abnormal blood counts such as chloromycetin
use and ionizing radiation.
(6) Both antibiotics are available as POMs (eg, Chloromycetin
Eye Ointment and Fucithalmic) and the former is also now widely available as P Medicines (eg, Optrex Infected Eyes antibiotic drops, GoldenEye antibiotic ointment and Brochlor antibiotic ointment).