chlorhexidine

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chlorhexidine

 [klor-hek´sĭ-dēn]
an antibacterial compound used in antimicrobial skin cleansers for surgical scrub, preoperative skin preparation, and cleansing skin wounds.

chlorhexidine

A disinfectant agent widely used in surgery for preoperative skin cleansing and for sterilizing instruments by soakage. The drug is on the WHO official list. A brand name is Hibitane.

antiseptic 

An agent that kills or prevents the growth of bacteria. This term is generally restricted to agents that are sufficiently non-toxic for superficial application to living tissues. These include the preservatives for eye drops and contact lens solutions. Examples of antiseptics are alcohol, benzalkonium chloride, cetrimide, chlorbutanol, chlorhexidine, hydrogen peroxide, thimerosal (or thiomersalate). Other agents that are too toxic to be applied to living tissues are called disinfectants and are used to sterilize instruments and apparatus. See disinfection; ethylenediamine tetraacetic acid; neutralization; sterilization.

chlor·hex·i·dine

(klōr-heksi-dēn)
A bis-biguanide useful as a topical antiseptic. The gluconate form is used as an oral rinse to inhibit oral bacteria in some conditions.
References in periodicals archive ?
The spectrum of organisms growing as contaminants on use of toothbrushes in the different storage conditions and effect of the Chlorhexidine gluconate 0.2 % is being shown in table 1.
mutans were sensitive against several active substances containing in commercial mouthwash such as chlorhexidine gluconate, mixture of thymol, eukaliptol, menthol, and methyl salicylate, and povidone-iodine at minimal concentration 0.5%.
Cost-benefit analysis of chlorhexidine gluconate dressing in the prevention of catheter-related bloodstream infections.
Similarly, the common side effects of chlorhexidine gluconate were staining of tongue and dental fillings and soreness of oral mucosa.24-25 These effects are comparatively mild, local and easy to manage.
Conclusion: Chlorhexidine gluconate was associated with lower infection rates compared to povidone-iodine; but it was not statistically significant.
(3) Evidence shows that the long--term twice daily use of 0.12% chlorhexidine gluconate (Peridex[R]; 3 M ESPE, Minneapolis, Minn) and essential oils and methyl salicylate (Listerine[R]; McNeil-PPC, Inc, Skillman, NJ), both anti-plaque and anti-gingivitis mouth rinses approved by the Council on Dental Therapeutics of the American Dental Association (ADA), do not have a negative effect on the oral microbial flora.
In this case the reduction in infection rates could be due to alcohol alone, rather than the independent variable of 2% chlorhexidine gluconate with 70% isopropyl alcohol.
Traditional methods of surgical hand antisepsis involve the use of a brush and sponge with either chlorhexidine gluconate 4% or povidone iodine 10%.
It comes in a convenient 500 mL pump bottle, is compatible with chlorhexidine gluconate (CHG), and both latex and non-latex gloves.
Oral rinses containing chlorhexidine gluconate exert antibacterial effects for up to 48 hours and are recommended--with your vet's consent, of course.
Chlorhexidine gluconate has been available to dentists for years.