Chinese Hamster Ovary Cell

(redirected from Chinese hamster ovary)
Also found in: Acronyms.
A line of fibroblasts isolated in 1958, which is used in research, grows well in culture, and spontaneously transforms to a malignant morphology, due to cytoskeletal disorganization
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2013) Engineering the cellular protein secretory pathway for enhancement of recombinant tissue plasminogen activator expression in Chinese hamster ovary cells: effects of CERT and XBP1s genes.
Transient Gene Expression (TGE) is a well-established technology for rapid production of milligram to gram quantities of recombinant proteins in Human Embryonic Kidney (HEK) and Chinese Hamster Ovary (CHO) cell lines (1-3) Due to quick turnover and low cost, TGE platform plays more important role in bio pharmaceutical early development stages for two reasons; Firstly, it is essential for large biopharmaceutical companies to screen multiple drug candidates prior to moving forward into the formal development pipeline.
1 Horse 1 V1 21 V2 21 2 Guinea pig 4 V3 21 V4 21 V5 21 3 Ferret 2 V6 21 V7 21 4 Ferret 2 V8 194 V9 194 V10 194 * HEK, human embryonic kidney cells; CHO, Chinese hamster ovary cells.
The Chinese hamster ovary (CHO) cells were kindly supplied by Professor Salvadori (UNESP-Botucatu.
Glycosylation defects alter insulin but not insulin-like growth factor 1 binding to Chinese hamster ovary (CHO) cells.
Chinese hamster ovary (CHO) cells are of great interest for bio processing and pharmaceutical research and development [1].
9 November 2010 - US biotechnology company Momenta Pharmaceuticals Inc (NASDAQ: MNTA) said yesterday it found that Chinese Hamster Ovary (CHO) cells contain the active biosynthetic machinery to produce alpha-Gal antigens and that a therapeutic protein manufactured in CHO contains alpha-Gal in studies.
Expression of biologically active human follitropin in chinese hamster ovary cells.
Because dornase alfa is produced in Chinese hamster ovary cells, the only contraindications have been in patients with sensitivity to these animal proteins.
Two cAMP controls, tested independent of the Chinese hamster ovary cells for 140 runs, had a CV of 15%.
The DNA for Cricetulus griseus (Chinese hamster) was obtained from Chinese hamster ovary (CHO) cells in the laboratory of Dr.

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