Initially while studying the activity of tumor suppressor p53 in Chinese hamster ovary cell line K1, we noticed in serendipity that mitotic inhibitor, colcemid, caused a moderate increase of UV-induced cell death .
Mark Azam, VP of R & D and Operations of HumanZyme added, "Life science to date has been using proteins derived from bacteria and Chinese hamster ovary cells. There is a limit to how much we can understand humans using nonhuman tools," said Li.
A report in Science Translational Medicine suggests that the antibody cocktail used in Ebola virus-infected patients can be further simplified to only two antibodies and that these antibodies can be produced in engineered Chinese hamster ovary cells. Such a cocktail protected nonhuman primates against the virus responsible for the 2014-2015 outbreak up to 3 days after exposure, and combining these antibodies with those specific for other strains may lead to a broad Ebola virus therapy.