Chinese Hamster Ovary Cell


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A line of fibroblasts isolated in 1958, which is used in research, grows well in culture, and spontaneously transforms to a malignant morphology, due to cytoskeletal disorganization
References in periodicals archive ?
Development of a serum-free culture medium for the large scale production of recombinant protein from a Chinese hamster ovary cell line.
Proteomic profiling of a high-producing Chinese hamster ovary cell culture," Anal Chem.
A cloned recombinant Chinese hamster ovary cell line (CHO-EPO) manipulated to secrete recombinant human erythropoietin was used in this work.
Influence of Primatone RL Supplementation on Sialylation of Recombinant Human Interferon-g Produced by Chinese Hamster Ovary Cell Culture Using Serum-Free Media," Biotechnol.
Acknowledgments: We thank Leonard Kohn for providing the Chinese hamster ovary cell line expressing the TSH receptor (Leonard Kohn, The Interthyr Research Foundation), Linda Seiler for excellent technical expertise, Hayden Jeffreys for samples from Graves patients (Kronus), and Lois Hybl and Tom Martins for critical reading of the manuscript.
Oligosaccharide structures present on asparagine-289 of recombinant human plasminogen expressed in a Chinese hamster ovary cell line.
Glutathione S-transferase in an arsenic-resistant Chinese hamster ovary cell line.
It was also decided that the mutant cell lines and the original Chinese Hamster Ovary cell line were possibly not apoptotic, that is, the cells do not participate in programmed cell death.
The FDA placed a clinical hold on IB1001 in July 2012 when a number of study subjects developed antibodies to the host cell protein, Chinese Hamster Ovary cell proteins (CHOP), of IB1001.
A report in Science Translational Medicine suggests that the antibody cocktail used in Ebola virus-infected patients can be further simplified to only two antibodies and that these antibodies can be produced in engineered Chinese hamster ovary cells.
Chinese hamster ovary cells were used for production of recombinant UL128 protein and the target protein was obtained through His-Bind Kit (Novagen, Germany).
What followed was a year of MS-adventures: "accidentally" kicking an officious male doctor in the crotch, becoming an undercover agent to pay for medication made from Chinese hamster ovary cells, discovering the amazing effects of legal speed, and battling her arch-nemesis, the dreaded food group: vegetables.

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