checkpoint

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checkpoint

In molecular and cell biology, a process or chemical that temporarily blocks or slows a biochemical event. Checkpoint mutations are associated with the unregulated growth of some cancers.

checkpoint

points in the cell cycle of eukaryotic cells which prevent progress until each stage is satisfactorily completed.
References in periodicals archive ?
It was a little bit of everything,'' said Deputy Dennis Campbell, one of the officers who manned the four-hour checkpoint Tuesday night on Sierra Highway south of Avenue L.
7) To this end, agencies using checkpoints must have a written policy as a directive for their officers to follow.
NASDAQ: ARQL) today provided an update on its clinical trials with three compounds: ARQ 197, a proprietary, orally administered small molecule inhibitor of the c-Met receptor tyrosine kinase; ARQ 501, a first-generation Activated Checkpoint Therapy(SM) (ACT) candidate; and ARQ 171, a second generation ACT compound.
The checkpoints will delay drivers for about a minute on average, though some will take up to three minutes, said Risinger.
Managers can tailor the roadblock by regulating the number of vehicles that can be stopped at any one time and by limiting the nature and number of questions posed by officers staffing the checkpoints.
The Court in Sitz began by acknowledging that all checkpoints, which by definition involve a "governmental termination of freedom of movement through means intentionally applied,"(7) constitute seizures under the Fourth Amendment and must, therefore, be reasonable.
Each registered hotel guest, including minors, who wants to gain access beyond the screening checkpoint, must first notify the hotel's Front Desk staff in person.
Smiths Detection, a world leading provider of trace detection and X-ray security screening equipment, today announced it has partnered with the Technical Support Working Group (TSWG) and the Transportation Security Administration (TSA) to design, develop and pilot a unique, movable security checkpoint called the Mobile Screening Checkpoint 40 (MSC 40).
With the initiation of these studies, we are taking an important step toward the clinic with a second compound from our E2F1 checkpoint pathway program, based on our alliance with Roche," said Dr.
The lab's aim is to identify technology solutions that may dramatically improve checkpoint security while driving down the total cost of ownership for government and airport operators around the world.
ArQule's fundamental approach to treating cancer is to restore the natural biological function of these checkpoints and thereby to kill cancer cells selectively while maintaining the integrity and function of healthy cells, thus avoiding the undifferentiated damage caused, for example, by chemotherapy or radiation.
Checkpoint Systems is very proud to support Metro's long-term, strategic investment in RFID," said George Off, CEO and Chairman of the Board of Checkpoint Systems, Inc.