Checkerboard Assay

A type of Boyden chamber assay for leukocyte chemotaxis, first introduced by Zigmond
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In vitro synergy testing using E-test and checkerboard assay (CBA)
Isolates showing additive were significantly more in tazobactam plus meropenem (in checkerboard assay 12 [22.
Data from checkerboard assay were analysed and interpreted using the fractional inhibitory concentration index and the response surface approach using the [DELTA]E model.
The checkerboard assay was carried out as described by Lorian (2005) with slight modifications as stated in the broth microdilution method above (Lorian 2005).
Fractional inhibitory concentration (FIC) from checkerboard assay of ceftazidime plus clavulanic acid, apigenin.
The checkerboard assay described by Verma (2007) was followed with modifications.
Table 2 shows MICs and FIC index from checkerboard assay of [beta]-lactam use alone and in combination with test flavonoids (galangin, quercetin and baicalein) or clavulanic acid against clinical isolates of S.
The checkerboard assay demonstrated that combinations of 1,8-cineole and aromadendrene reduce the MIC in most cases in an additive way, whereas the time-kill assay indicates a synergistic effect.