chloroform

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chloroform

 [klor″o-form]
a colorless, mobile liquid with an ethereal odor and sweet taste, used as a solvent; it is hepatotoxic and nephrotoxic when ingested. It was once used widely medicinally, such as for inhalation anesthesia and analgesia.

chlor·o·form

(klōr'ō-fōrm),
Formerly used by inhalation to produce general anesthesia; also used as a solvent.
Synonym(s): trichloromethane
[chlor(ine) + form(yl)]

chloroform

/chlo·ro·form/ (klor´ah-form) a colorless, mobile liquid, CHCl3, with an ethereal odor and sweet taste, used as a solvent; once widely used as an inhalation anesthetic and analgesic, and as an antitussive, carminative, and counterirritant. It is hepatotoxic and nephrotoxic by ingestion.

chloroform

(klôr′ə-fôrm′)
n.
A clear, colorless, dense, sweet-smelling liquid, CHCl3, used in refrigerants, propellants, and resins, as a solvent, and sometimes as an anesthetic. Chloroform, once widely used in human and veterinary surgery, has generally been replaced by less toxic, more easily controlled agents.
tr.v. chloro·formed, chloro·forming, chloro·forms
1. To treat with chloroform to anesthetize, render unconscious, or kill.
2. To apply chloroform to.

chloroform

[klôr′əfôrm′]
Etymology: Gk, chloros + L, formica, ant
1 a nonflammable volatile liquid that was the first liquid inhalation anesthetic to be discovered. (Nitrous oxide was the first gaseous inhalation anesthetic agent discovered.) Chloroform has a low margin of safety and significant toxicity. The drug is not used in the United States.
2 a solvent that is hepatotoxic and nephrotoxic if ingested.

chlor·o·form

(klōr'ō-fōrm)
Formerly used by inhalation to produce general anesthesia; also used as a solvent.
[chlor(ine) + form(yl)]

chloroform

A heavy, colourless, volatile liquid once widely used as a pleasant and easy general anaesthetic but now abandoned because of its tendency to cause CARDIAC ARREST and other dangerous complications including delayed liver atrophy.

chlor·o·form

(klōr'ō-fōrm)
Formerly used inhalation agent to produce general anesthesia; also used as a solvent.

chloroform,

n a nonflammable, volatile liquid that was the first inhalation anesthetic to be discovered. It is no longer in general use because of its inherent risk factors and low margin of safety.

chloroform

CHCl3; a liquid with an ethereal odor and sweet taste, used as a solvent; once used widely as an inhalation anesthetic and analgesic, and as an antitussive, carminative and counterirritant. An effective but dangerous anesthetic used commonly at one time especially in horses. Requires a proper mask. Prolonged anesthesia often results in severe liver damage.
References in periodicals archive ?
Preliminarily, two phase solvent extraction experiments were carried out in CHCl3 without calixarenes to optimize and diminish the effect of solvent for the transfer of reactive dye from aqueous phase to organic phase at different pH of the solution (i.
The fraction D (3g) of the main column, which was eluted with n-hexane: CHCl3 (3: 7), on repeated silica gel column chromatography yielded compound 9 (170 mg), 10 (90 mg) and 11 (22 mg) when eluted with n-hexane: CHCl3 (5: 5, 6: 4 and 7: 3 respectively).
5 g) obtained with n-hexane: CHCl3 (8: 2) was again subjected to silica gel column chromatography using gradient of n-hexane: CHCl3 to get three sub-fractions (A1-A3).
P:>270degC,Colour: offwhite, Solubility: CHCl3, Mass: MSm/z:391.
65g (56 %) M P: 240 degC Colour: yellow Solubility: CHCl3, Mass:MS m/z :456[M+],379[M+-C6H5] 215 [M+-C12H14 N 2 O2].
It is unstable in hot benzene as well as in CHCl3 where the free ligand is formed slowly (Scheme-2).
diethyl ether, CHCl3, Na2CO3, MgSO4 were purchased from Merck and Fluka and were used without further purification.