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A gene on chromosome 6p12 that encodes a member of the AP-2 family of transcription factors, which activate the transcription of genes involved in proper eye, face, body wall, limb and neural tube development. TFAP2B inhibits C/EBP alpha, MCAM/MUC18 and MYC; it appears to be required for normal face and limb development, and for proper terminal differentiation and function of renal tubular epithelia.

Molecular pathology
TFAP2B mutations cause autosomal dominant Char syndrome.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The meeting decided that people would gather at Charing Cross, Regal Chowk and Civil Secretariat Chowk in Lahore while there would also be gatherings at divisional headquarters, districts and tehsils.
When the Jubilee line was extended to Stratford, there was found no need for its Charing Cross stop, and it was abandoned.
In October Tammie and Richard are running the Cardiff Half Marathon together to raise funds for Charing Cross Hospital, where she was treated.
By the time the train reached Charing Cross, I was left cursing myself for having opted for that beige jacket and not one of my favourite Ts.
Commuters were the ultimate sufferers of the protest, barricades were placed on Queen's Road and Lawrence Road to deal with the sit-in, resultantly, huge traffic diversions ended up inconveniencing commuters.QueensRoad, Faisal Chowk (Charing Cross) and Lawrence Road became hostage to disruptive demonstrations and traffic snarls.
A British Transport Police spokesman said: "We are currently dealing with an incident at Charing Cross station following reports of a man on the tracks claiming to have a bomb.
British Transport Police tweeted: "We are currently dealing with an incident at Charing Cross station following reports of a man on the tracks claiming to have a bomb.
The post Charing Cross station evacuated after bomb scare, man arrested appeared first on Cyprus Mail .
Merseyside Police's contact centre said in a tweet: "Please be advised Police are currently dealing with a Road Traffic Collision on Charing Cross, with the junction of Exmouth Street.
The drama has been written and directed by Shahid Mahmood Nadeem on political and social events, occurring at Charing Cross during the past decades.
The railway operator said Charing Cross and Waterloo East stations would remain closed, with some services diverted to other stations and others likely to be cancelled.
Workers are evacuated from offices on a street adjoining The Strand in central London yesterday after a gas leak closed The Strand and Charing Cross railway station.