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A gene on chromosome 6p12 that encodes a member of the AP-2 family of transcription factors, which activate the transcription of genes involved in proper eye, face, body wall, limb and neural tube development. TFAP2B inhibits C/EBP alpha, MCAM/MUC18 and MYC; it appears to be required for normal face and limb development, and for proper terminal differentiation and function of renal tubular epithelia.

Molecular pathology
TFAP2B mutations cause autosomal dominant Char syndrome.


arctic and subarctic species of the fish genus salvelinus.
References in periodicals archive ?
Within the newly-widened chare the building steps back to open up toward the listed almshouses and the public courtyard space behind.
They may have been narrow, dark and horrible places to live but they had beautiful names such as Peppercorn Chare and Blue Anchor Chare," he said.
It also includes a new chare, or small street, between Newgate Street and Falconer's Court, leading on to Fenkle Street and which would provide access to the hotels.