Chagas disease


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South A·mer·i·can try·pan·o·so·mi·a·sis

trypanosomiasis caused by Trypanosoma (or Schizotrypanum) cruzi and transmitted by certain species of reduviid (triatomine) bugs. In its acute form, it is seen most frequently in young children, with swelling of the skin at the site of entry, most often the face, and regional lymph node enlargement; in its chronic form it can assume several aspects, commonly cardiomyopathy, but megacolon and megaesophagus also occur; natural reservoirs include dogs, armadillos, rodents, and other domestic, domiciliated, and wild mammals.

South A·mer·i·can try·pan·o·so·mi·a·sis

(sowth ă-mer'i-kăn trī-pan'ō-sŏ-mī'ă-sis)
Disease caused by Trypanosoma (or Schizotrypanum) cruzi and transmitted by some species of reduviid (triatomine) bugs. In its acute form, it is seen most frequently in young children, with swelling of the skin at the site of entry, most often the face, and regional lymph node enlargement; in its chronic form it can assume several aspects, commonly cardiomyopathy, but megacolon and megaesophagus also occur; natural reservoirs include domestic, domiciliated, and wild mammals.
Synonym(s): Chagas disease, Chagas-Cruz disease, Cruz trypanosomiasis.

Chagas disease

(shag'as)
[Carlos Ribeiro Justiniano Chagas, Brazilian physician, 1879–1934]
A bloodborne disease caused by Trypanosoma cruzi and transmitted by the biting of a reduviid bug. It is characterized by fever, lymphadenopathy, hepatosplenomegaly, and facial edema. Chronic cases may be mild or asymptomatic, or may be accompanied by myocarditis, cardiomyopathy, megaesophagus, megacolon, or death.

Etiology

Chagas disease may be transmitted from person-to-person by needlestick injury, transfusion, organ donation, or during childbirth.

Synonym: American trypanosomiasis; South American trypanosomiasis See: Trypanosoma cruzi

Chagas,

Carlos J.R., Brazilian physician and parasitologist, 1879-1934.
Chagas disease - parasitic infection transmitted by certain species of reduviid (triatomine) bugs. Synonym(s): Chagas-Cruz disease; Chagas-Mazza disease; Cruz trypanosomiasis; South American trypanosomiasis
Chagas-Cruz disease - Synonym(s): Chagas disease
Chagas-Mazza disease - Synonym(s): Chagas disease

Mazza,

Salvador, Argentinian physician, 1886-1946.
Chagas-Mazza disease - Synonym(s): Chagas disease
References in periodicals archive ?
Caryn Bern, a professor of epidemiology and biostatistics at the University of California, said, "Early detection of Chagas disease is critical, allowing prompt initiation of therapy when the evidence for cure is strong."
The terms employed for the search were previously selected considering the controlled vocabulary for indexing papers of the Health Sciences Descriptors (DeCS) and the Medical Subject Headings (MeSH) system, through which descriptors "Chagas disease" and "Quality of Life" were captured, used in SciELO and Lilacs and "Chagas Disease" and "Quality of Life", corresponding to PubMed.
Chagas disease in the state of Amazonas: history, epidemiological evolution, risks of endemicity and future perspectives.
Therefore, it is worth emphasizing the need to understand how the Brazilian health services and their professionals have been meeting the healthcare demands in the contexts of migration flows, notably referring to Chagas disease.
[2] World Health Organization (WHO), Preventing Mother-to-Child Transmission of Chagas disease: from Control to Elimination, WHO: Neglected tropical disease, 2018.
Subjects with any of the following conditions were excluded from the study: previous treatment with benznidazole, coinfectious diseases, pregnancy, autoimmune diseases, cancer, and associated cardiovascular diseases that hampered the classification of the cardiac form of Chagas disease or the associated digestive form of Chagas disease.
This research aimed to identify potential barriers to healthcare access for Chagas disease in Colombia, defined as diagnosis, from the perspective of healthcare providers, and, additionally, to systematically review the literature on the views of healthcare professionals to the access to healthcare for Chagas disease and to identify potential barriers.
The early identification of areas with greater (or significant) vulnerability to the occurrence of synanthropic triatomines and transmission of human Chagas disease is fundamental for the design and application of efficient and economically viable intervention actions [25].
Evaluation of the ELISA-F29 test as an early marker of therapeutic efficacy in adults with chronic Chagas disease. Revista do Instituto de Medicina Tropical de Sao Paulo, 55, 167-172.
M2 EQUITYBITES-September 1, 2017-Chemo Group awarded US FDA approval of life-saving medical treatment benznidazole in aid of people with Chagas disease
Eisai is proactively collaborating with academia and research organizations and has participated in 11 joint research projects to develop new medicines and vaccines for malaria, Chagas disease, leishmaniasis, and filariasis, with the support of the GHIT Fund.