cetirizine

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cetirizine

 [sĕ-tir´ĭ-zēn]
a nonsedating antihistamine administered orally in the form of the hydrochloride salt for treatment of allergic rhinitis and chronic hives, and as a treatment adjunct for asthma.

cetirizine

/ce·ti·ri·zine/ (sĕ-tir´ĭ-zēn) a nonsedating antihistamine used as the hydrochloride salt in the treatment of allergic rhinitis, chronic idiopathic urticaria, and asthma.

cetirizine

(sə-tîr′ə-zēn′)
n.
A nonsedating antihistamine, C21H25ClN2O3, used in the form of its hydrochloride to treat allergic rhinitis and other allergic disorders.

cetirizine

an H1-histamine antagonist.
indications It is used to treat allergy symptoms and rhinitis.
contraindications Known hypersensitivity to this drug, lactation, and severe hepatic disease prohibit its use. It also should not be used in newborns or premature infants.
adverse effects Life-threatening effects include hemolytic anemia, thrombocytopenia, leukopenia, agranulocytosis, pancytopenia, and dysrhythmias (rare). Other serious adverse effects include urinary retention, impotence, diarrhea, vomiting, sedation, confusion, blurred vision, tremors, hypotension, palpitations, bradycardia, and tachycardia. Common side effects are thickening of bronchial secretions, nausea, drowsiness, and headache.

cetirizine

Zyrtec® Therapeutics A potent, antiinflammatory H1-receptor antagonist used for respiratory allergies; it has little CNS reactivity or cardiotoxicity and doesn't interact with other medicines. See Antihistamine.

cetirizine

An ANTIHISTAMINE drug used in the treatment of hay fever and other allergic conditions. A brand name is Zirtek Allergy.

antihistamine 

Any substance that reduces the effect of histamine or blocks histamine receptors, usually the histamine 1 (H1) receptor. It is used in the treatment of allergic conjunctivitis and also in the temporary relief of minor allergic symptoms of the eye. Common agents include antazoline sulfate, azelastine hydrochloride, cetirizine, chlorphenamine, emedastine, epinastine hydrochloride, ketotifen, levocabastine, loratadine and olopatadine. See hypersensitivity; mast cell stabilizers.
References in periodicals archive ?
Hydro-alcoholic gels (20 g each) of cetirizine HCl with various concentrations of PG and PEG were formulated (Khan et al.
A carefully weighed quantity of cetirizine HCl was dissolved in distilled water in 100 ml of volumetric flask.
Cetirizine HCl shows a maximum absorbance at 231 Lambdamax.
concentration (ug/ml) of cetirizine HCl, y is absorbance at 231 nm and R2 correlation coefficient.
The appearance and other physical properties, including clarity, homogeneity consistency and spreadibility of the prepared Cetirizine HCl gel were inspected (Shah et al.
In order to determine the spreadibility of the prepared cetirizine HCl gels about 0.
In order to determine the pH of cetirizine HCl gels about 1 gm of prepared gel was dissolved in 100 ml of distilled water and shaked it well and then determine the pH by using digital pH meter (WTW, pH 526, Germany).
Determination of drug content of cetirizine HCl gels Standard solutions was prepared by dissolving and diluting 200mg of Cetirizine HCl working standard in 100 ml of 0.
For sample preparation, weigh powder sample equivalent to 200 mg of cetirizine HCl.
The solubility (ug/ml) of cetirizine HCl was 24347, 19913 and 0.
Table I illustrates the cumulative amount of cetirizine HCl permeated via silicone membrane using various formulations.
A small amount of cetirizine HCl was dissolved in 10 ml of distilled water in separating funnel, shaked it for 10 min, added 10 ml of octanol and shaked vigorously for 10 min.