sensitization

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sensitization

 [sen″sĭ-tĭ-za´shun]
2. exposure to allergen that results in the development of hypersensitivity.
3. the coating of erythrocytes with antibody so that they are subject to lysis by complement in the presence of homologous antigen, the first stage of a complement fixation test.
autoerythrocyte sensitization see autoerythrocyte sensitization syndrome.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

sen·si·ti·za·tion

(sen'si-ti-zā'shŭn),
1. Immunization, especially with reference to antigens (immunogens) not associated with infection; the induction of acquired sensitivity or of allergy.
2. In substance use/abuse parlance, the increased response seen to subsequent administration of the substance.
Farlex Partner Medical Dictionary © Farlex 2012

sensitization

Immunology The process in which a person acquires the ability to react to an antigen, usually of nonself origin. See Secondary–immune response. Cf Primary–immune response.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

sen·si·ti·za·tion

(sen'si-tī-zā'shŭn)
Immunization, especially with reference to antigens (immunogens) not associated with infection; the induction of acquired sensitivity or of allergy.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

sensitization

The preliminary exposure of a person to an ALLERGEN that leads to ANTIBODY production by the immune system and, on subsequent exposure, to an ALLERGIC or hypersensitivity reaction. Immunoglobulin Type E (IgE) is the main type of antibody involved.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

sensitization

the state in which an enhanced IMMUNE RESPONSE is provoked by a second exposure to an ANTIGEN. This may be an allergic response (see ALLERGY).
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

sensitization 

1. A state or condition in which the response to a second or later stimulus (e.g. a drug) is greater than the response to the original stimulus (e.g. first administration of the drug). 2. The process in which exposure to an antigen results in the development of hypersensitivity.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann

sen·si·ti·za·tion

(sen'si-tī-zā'shŭn)
1. Immunization, especially with reference to antigens (immunogens) not associated with infection; induction of acquired sensitivity or of allergy.
2. In substance use/abuse parlance, increased response seen to subsequent administration of the substance.
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about sensitization

Q. I had cataract surgery with iol implant, and ever since I have awful light sensitivity. Any ideas? I can't go into a "super store" without my sunglasses. My eyes ache at the end of the day. My doctor says "I don't know!"

A. May sound a bit silly question, but have you tried to consult your ophthalmologist (eye doctor, e.g. the one that performed the operation) about it? Cataract surgery, although considered very successful, isn't problem-free. Primary physician may not have the necessary specialization to deal with these subjects.

Q. I heard that patients are highly sensitive to their senses? what are the most common symptoms of fibromyalgia and can they be aggravated? I heard that patients are highly sensitive to their senses?

A. Great answeer...couldn't agree more!

Q. when my aunt went through chemo (for colon cancer) her palms became VERY sensitive and had a burning feeling is there any way to prevent this from happening to my mom who is starting her chemo now? If not, what it the best treatment for it?

A. What you describe sounds like peripheral neuropathy, a well known side effect of platinum chemotherapy which is used for colon cancer. Several measures, including giving infusion of calcium and magnesium, and glutathione were found to reduce the rate of this complication, although further studies are necessary.

However, the information is only general advice, since I haven't examined your mother so if you have any questions about this subject, it may be wise to consult a doctor (e.g. oncologist).

You may read more here:
http://www.nlm.nih.gov/medlineplus/cancerchemotherapy.html

More discussions about sensitization
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References in periodicals archive ?
Similar to the pathophysiological mechanisms of migraine, IBS recurrently activates the intestinal nervous system, leading to C-FOS expression in the brain stem and causing central sensitization.20,21
The diagnosis then becomes pain primarily related to RA with central sensitization, and both need to be addressed in a treatment plan.
Woolf, "The contribution of GABAA and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord," Journal of Neurophysiology, vol.
One of the possible mechanisms associated with hyperalgesia after NTG administration consists in central sensitization induced by NO released from NTG.
Woolf CJ (2007) Central sensitization: uncovering the relation between pain and plasticity.
Treatment of Myofascial pain syndrome is difficult because it may be initiated by peripheral and central mechanisms that appear to be inter-related as Central sensitization would lead to an increased excitability of spinal and supraspinal regions resulting from injury or inflammation-induced activation of peripheral nociceptors.
A new study reports that patients with knee osteoarthritis (OA) who have poor sleep habits display greater central sensitization"an amplification of clinical pain.
TEHRAN (FNA)- Sleep disruption appears to be associated with altered pain processing and central sensitization, according to research.
Another aspect of central sensitization is the dysfunction in pain inhibition [8].
Studies on animals have demonstrated that NO enhances the sensitivity of peripheral nociceptors (10) and can contribute to hyperalgesia secondary to central sensitization (11).
For years, researchers have been trying to elucidate the molecular mechanisms that underlie central sensitization to develop novel approaches for treating chronic pain conditions.

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